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Gut microbiota alteration in a mouse model of Anorexia Nervosa
Authors:Jonathan Breton  Pauline Tirelle  Soujoud Hasanat  Arthur Pernot  Clément L'Huillier  Jean-Claude do Rego  Pierre Déchelotte  Moïse Coëffier  Laure B. Bindels  David Ribet
Affiliation:1. Normandie Univ, UNIROUEN, INSERM UMR1073, Nutrition, inflammation et dysfonction de l''axe intestin-cerveau, Rouen, France;2. Normandie Univ, UNIROUEN, Institute for Research and Innovation in Biomedicine (IRIB), Rouen, France;3. Normandie Univ, UNIROUEN, Behavioural Analysis Platform (SCAC), Rouen, France;4. Rouen University Hospital, Nutrition Department, Rouen, France;5. Metabolism and Nutrition Research Group, Louvain Drug Research Institute, Université catholique de Louvain, Brussels, Belgium;1. Centre of Research in Epidemiology and Statistics Sorbonne Paris Cité, Obstetrical, Perinatal and Pediatric Epidemiology Research Team (EPOPé), Inserm UMR 1153, Labex GR-Ex, Paris Descartes University, France;2. Department of General Pediatrics and Pediatric Infectious Diseases, Necker-Enfants Malades Hospital, AP-HP, Paris Descartes University, Paris, France;3. Association Française de Pédiatrie Ambulatoire (AFPA), Talence, France;4. Comité de Nutrition de la Société Française de Pédiatrie, Paris, France;5. Centre of Research in Epidemiology and Statistics Sorbonne Paris Cité, Nutritional Epidemiology Research Team (EREN), Inserm UMR 1153, Paris Descartes University, Sorbonne Paris Cité, France;6. Département de Santé Publique, AP-HP, Hôpital Avicenne, Bobigny, France;7. Centre de Recherche sur l''inflammation, Inserm UMR 1149, Université Paris Diderot, ERL CNRS 8252, Faculté de Médecine Site Bichat, Paris, France;8. Laboratoire CERBA, Saint-Ouen l’Aumône, France;9. Centre de Recherche pour l''Etude et l''Observation des Conditions de vie (CREDOC), Paris, France;10. Centre Régional de Coordination des dépistages des Cancers Ile-de-France, Lieusaint, France;11. AFPA, Essay Les Nancy, France;12. AFPA, Nantes, France;13. AFPA, Vichy, France;14. Association Clinique et Thérapeutique Infantile du Val-de-Marne (ACTIV), Saint-Maur des Fossés, France;15. Université Paris Est, IMRB- GRC GEMINI, 94000, Créteil, France;1. State Key Laboratory of Oncogenes and Related Genes, Center for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai 20025, PR China;2. State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China;3. Pôle de Recherches Sino-Françaisen Science Du Vivant et Génomique, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China;4. CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China;1. Department of Medicine, University of Udine, 33100, Udine, Italy;2. Department of Medical Oncology, Unit of Medical Oncology and Cancer Prevention, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, 33081, Aviano, Italy;3. Experimental and Clinical Pharmacology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, 33081, Aviano, Italy;4. Department of Research and Diagnosis, Division of Molecular Oncology, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy;5. Scientific Directorate, Centro di Riferimento Oncologico (CRO), IRCCS, 33081, Aviano, Italy;6. Department of Oncologic Radiation Therapy and Diagnostic Imaging, Centro di Riferimento Oncologico, Via Franco Gallini, 2, 33081, Aviano, Italy;7. Department of Oncology, San Bortolo General Hospital, 36100, Vicenza, Italy
Abstract:
Keywords:Anorexia nervosa  Eating disorders  Gut microbiota  Activity-based anorexia  Food restriction  Physical activity
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