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Risks of nonchromosomal birth defects,small-for-gestational age birthweight,and prematurity with in vitro fertilization: effect of number of embryos transferred and plurality at conception versus at birth
Authors:Luke  Barbara  Brown  Morton B.  Wantman  Ethan  Forestieri  Nina E.  Browne  Marilyn L.  Fisher  Sarah C.  Yazdy  Mahsa M.  Ethen  Mary K.  Canfield  Mark A.  Nichols  Hazel B.  Oehninger  Sergio  Doody  Kevin J.  Sutcliffe  Alastair G.  Williams  Carrie  Eisenberg  Michael L.  Baker  Valerie L.  Sacha  Caitlin R.  Lupo  Philip J.
Affiliation:1.Department of Obstetrics, Gynecology, and Reproductive Biology, College of Human Medicine, Michigan State University, 965 Wilson Road, East Fee Hall, Room 628, East Lansing, MI, 48824, USA
;2.Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI, USA
;3.Redshift Technologies, Inc., New York, NY, USA
;4.Birth Defects Monitoring Program, State Center for Health Statistics, North Carolina Department of Health and Human Services, Raleigh, NC, USA
;5.Birth Defects Research Section, New York State Department of Health, Albany, NY, USA
;6.Department of Epidemiology and Biostatistics, School of Public Health, University at Albany, Rensselaer, NY, USA
;7.Massachusetts Center for Birth Defects Research and Prevention, Massachusetts Department of Public Health, Boston, MA, USA
;8.Birth Defects Epidemiology and Surveillance Branch, Texas Department of State Health Services, Austin, TX, USA
;9.Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA
;10.Virginia Beach, USA
;11.Center for Assisted Reproduction, Bedford, TX, USA
;12.UCL Great Ormond Street Institute of Child Health, University College London, London, UK
;13.Division of Male Reproductive Medicine and Surgery, Department of Urology, Stanford University School of Medicine, Palo Alto, CA, USA
;14.Division of Reproductive Endocrinology and Infertility, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA
;15.Massachusetts General Hospital Fertility Center and Harvard Medical School, Boston, MA, USA
;16.Epidemiology Program, Texas Children’s Cancer and Hematology Centers, Baylor College of Medicine, Houston, TX, USA
;
Abstract:
Journal of Assisted Reproduction and Genetics - Excess embryos transferred (ET) (> plurality at birth) and fetal heartbeats (FHB) at 6 weeks’ gestation are associated with reductions...
Keywords:In vitro fertilization (IVF)   Assisted reproductive technology (ART)   Birth defects   Embryos transferred   Fetal heartbeats   Vanishing twin syndrome
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