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| 紫杉醇联合异环磷酰胺治疗晚期非小细胞肺癌31例 | |
| 引用本文： | 徐绮腻,陈蕾,郑瑾,郑毓武. 紫杉醇联合异环磷酰胺治疗晚期非小细胞肺癌31例[J]. 汕头大学医学院学报, 2005, 18(4): 208-209 |
| 作者姓名： | 徐绮腻 陈蕾 郑瑾 郑毓武 |
| 作者单位： | 汕头大学医学院附属肿瘤医院内科,广东,汕头,515041 |
| 摘 要： | 目的：初步探讨紫杉醇联合异环磷酰胺治疗晚期非小细胞肺癌的疗效及毒副作用。方法：用紫杉醇联合异环磷酰胺治疗晚期非小细胞肺癌31例。紫衫醇（175mg／m^2d1）静滴3h，异环磷酰胺（1．5g/m^2 d1-3）静滴6～8h。21d为1个周期，连续2～6个周期。结果：完全缓解1例，部分缓解7例，稳定17例，进展6例。总有效率25．8％。毒副作用主要有WBC减少，脱发，恶心、呕吐，肌肉酸痛。结论：紫杉醇联合异环磷酰胺治疗晚期非小细胞肺癌疗效肯定。毒性可以耐受。 |
| 关 键 词： | 非小细胞肺癌 联合化疗 紫杉醇 异环磷酰胺 |
| 文章编号： | 1007-4716（2005）04-0208-02 |
| 收稿时间： | 2005-10-11 |
| 修稿时间： | 2005-10-11 |
Clinical Study of Paclitaxel Combined with Ifosfamide for 31 Patients of Advanced Non-small Cell Lung Cancer |
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| XU Qi-ni,CHEN Lei,ZHENG Jin,ZHENG Yu-wu. Clinical Study of Paclitaxel Combined with Ifosfamide for 31 Patients of Advanced Non-small Cell Lung Cancer[J]. Journal of Shantou University Medical College, 2005, 18(4): 208-209 | |
| Authors: | XU Qi-ni CHEN Lei ZHENG Jin ZHENG Yu-wu |
| Abstract: | Objective: To evaluate the curative effect and toxic side-effects of paclitaxel combined with ifosfamide in the treatment of advanced non-small cell lung cancer.Methods: Thirty-one patients were injected with intravenous infusion of paclitaxol(175 mg/m2d1)for 3 hours,and ifosfamide(1.5 g/m2d1~3)for 6~8 hours.Each cycle was 21 days.Re-sults: The overall effective rate was 25.8% with complete remission of one case and partial remission of 7 cases.The main toxic side-effets were leucopenia,alopenia,nausea and vomiting,muscle aching pain.Conclusion: Paclitaxel combined with ifosfamide is the effective method for advanced non-small cell lung cancer. |
| Keywords: | non-small cell lung cancer combined chemotherapy paclitaxel ifosfamide |
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