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Successful liver transplantation following veno-arterial extracorporeal membrane oxygenation in a child with fulminant Wilson disease and severe pulmonary hemorrhage: A case report |
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| Authors: | Son Seung Kook Oh Seak Hee Kim Kyung Mo Lee Yeoun Joo Jhang Won Kyoung Park Seong Jong Shin Hong Ju Park Jeong-Jun Kim Tae Hoon Kim Dae Yeon Hwang Shin Park Kwang-Min Lee Young-Joo Lee Sung-Gyu |
| Affiliation: | Department of Pediatrics Department of Pediatric Cardiac Surgery Department of Pediatric Surgery, Asan Medical Center Children's Hospital Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. |
| Abstract: | Son SK, Oh SH, Kim KM, Lee YJ, Jhang WK, Park SJ, Shin HJ, Park J‐J, Kim TH, Kim DY, Hwang S, Park K‐M, Lee Y‐J, Lee S‐G. Successful liver transplantation following veno‐arterial extracorporeal membrane oxygenation in a child with fulminant Wilson disease and severe pulmonary hemorrhage: A case report. Pediatr Transplantation 2011. © 2011 John Wiley & Sons A/S. Abstract: Massive pulmonary hemorrhage and other serious cardiopulmonary diseases in patients with fulminant hepatitis result not only in graft failure but also mortality after LT. ECMO is used to treat children with cardiorespiratory failure refractory to conventional intensive care. We describe a five‐yr‐old girl with genetically confirmed fulminant Wilson disease and severe pulmonary hemorrhage who underwent successful primary LT following veno‐arterial ECMO. To our knowledge, this is the first report of successful primary LT in a patient using veno‐arterial ECMO. The present case demonstrates that ECMO, as a bridging modality to LT, may be necessary to manage both massive pulmonary hemorrhage and possible graft loss because of hypoxemia. |
| Keywords: | acute liver failure fulminant hepatic failure pediatric liver transplantation Wilson’s disease respiratory insufficiency |
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