| HPLC测定麻杏止咳糖浆中盐酸麻黄碱的含量 |
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| 引用本文： | 景金柱,余卫兵,毕雪艳,郭迎霞. HPLC测定麻杏止咳糖浆中盐酸麻黄碱的含量[J]. 齐鲁药事, 2005, 24(7): 409-410 |
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| 作者姓名： | 景金柱 余卫兵 毕雪艳 郭迎霞 |
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| 作者单位： | 1. 邯郸康业制药有限公司,邯郸,056003
2. 邯郸市药品检验所,邯郸,056001 |
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| 摘 要： | 目的建立用高效液相色谱法测定麻杏止咳糖浆中盐酸麻黄碱含量的方法。方法采用十八烷基硅烷键合硅胶为填充剂,0.01mol·L-1磷酸二氢钾-甲醇(94∶6)为流动相,检测波长为210nm。结果盐酸麻黄碱进样量在0.3145～3.1450μg范围内呈现良好的线性关系,平均回收率为99.38%,RSD为0.59%(n=5)。结论本方法结果准确,重现性好,可用于麻杏止咳糖浆中盐酸麻黄碱的含量测定。
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| 关 键 词： | 高效液相色谱法 麻杏止咳糖浆 盐酸麻黄碱 含量测定 |
| 文章编号： | 1672-7738(2005)07-0409-02 |
HPLC determination of Ephedrine hydrochloride in Maxing Cough Syrup |
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| Jing Jin-zhu,YU Wei-bing,Bi Xue-yan,Guo Ying-xia. HPLC determination of Ephedrine hydrochloride in Maxing Cough Syrup[J]. qilu pharmaceutical affairs, 2005, 24(7): 409-410 |
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| Authors: | Jing Jin-zhu YU Wei-bing Bi Xue-yan Guo Ying-xia |
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| Affiliation: | Jing Jin-zhu,Yu Wei-bing 1,Bi Xue-yan 1,Guo Ying-xia 1 |
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| Abstract: | Objective To establish a method for determination of Ephedrine hydrochloride in Maxing Cough Syrup by HPLC.Methods C_ 18 column was used and the mobile phase was consisted of 0.01mol·L -1 potassium dihydrogen phosphate-methanol(94∶6).The detective wavelength was at 210nm.Results Average density of Ephedrine hydrochloride between 0.3145～3.1450μg,linear relationship is good,and average rate of recovery was 99.38%,RSD=0.59%(n=5).Conclusion The method is accurate,stable and can be used to determine Ephedrine hydrochloride in Maxing Cough Syrup. |
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| Keywords: | HPLC Maxing Cough Syrup Ephedrine hydrochloride content determination |
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