细支气管肺泡癌肿瘤直径对术中淋巴结清扫范围的可能价值

目的 初步探讨不同直径单发细支气管肺泡癌(bronchioloalveolar carcinoma,BAC)的淋巴结转移频度及区域间差别,以指导临床术中淋巴结清扫.方法 收集手术治疗、病理诊断为BAC的肺孤立性结节137例,根据肿瘤直径分为3组:≤2 cm组,2～3 cm组,＞3 cm组.分析组间N1、N2组淋巴结转移率的差异.结果 3组患者间N1组淋巴结转移率差异有统计学意义(P＜0.05),对于直径较大病变,术中应对第10组淋巴结完整清扫；3组患者间N2组淋巴结转移率差异无统计学意义.结论 BAC肿瘤直径可能对术中N1组淋巴结清扫更有指导价值.

Value of tumor diameter of bronchi-oloalveolar carcinoma for determining extent of lymph node dissection

Objective To study the metastasis frequencies and areas of solitary bronchioloalveolar carcinoma(BAC) of different diameters,so as to guide the intraoperative lymph node dissection.Methods A total of 137 patients with pathologically-confirmed solitary BAC received surgical treatment.The patients were divided into 3 groups according to tumor diameters: ≤2 cm group,2-3 cm group,and >3 cm group.The N1 and N2 lymph node metastasis rates of the 3 groups were analyzed.Results The N1 lymph node metastasis rates were significantly different between the 3 groups(P<0.05);for tumors with greater diameter,the tenth group lymph nodes should be completely dissected.The N2 lymph node metastasis rates were not significantly between the 3 groups(P<0.05).Conclusion The tumor diameter of BAC may be used to guide the dissection extent of N1 group lymph nodes,but not that of N2 group lymph nodes.