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| 脂质过氧化对内皮细胞和单核细胞间相互作用的影响 | |
| 引用本文： | 洪伟 陈铁镇. 脂质过氧化对内皮细胞和单核细胞间相互作用的影响[J]. 中国医科大学学报, 1994, 23(2): 88-92 |
| 作者姓名： | 洪伟 陈铁镇 |
| 摘 要： | 以巯基氧化剂联胺作用于培养人血管内皮细胞，引发细胞过氧化脂质蓄积与脂质过氧化损伤。结果发现，内皮细胞脂质过氧化损伤使单核细胞对内皮细胞的粘附增加，单核细胞主要粘附于受损伤的内皮细胞表面和间隙。揭示单核细胞对内皮细胞粘附增加，是内皮细胞脂质过氧化损伤促进和加重动脉粥样硬化病变形成的一个重要机制。 |
| 关 键 词： | 脂质过氧化；内皮细胞；单核细胞；动脉粥样硬化 |
Effect of Lipid Peroxidation on Interaction Between Endothelial Cell and Monocyte |
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| Hong Wei,Chen Tiezhen. Effect of Lipid Peroxidation on Interaction Between Endothelial Cell and Monocyte[J]. Journal of China Medical University, 1994, 23(2): 88-92 | |
| Authors: | Hong Wei Chen Tiezhen |
| Affiliation: | Laboratory of Experimental Pathology |
| Abstract: | ipid peroxidative injury to cultured endothelial cell(EC )from human umbilical vein was initiatedby treating EC with diamide.Results showed that EC injury and increased adherence of monocyte to ECwere observed with increased lipid peroxides. Monocyte appeared to prefer to adhere to the space andsurface of injured EC. These results suggested that the increased adherence of monocyte to EC injuredby lipid peroxidation may play an inportant role in atherogenesis. |
| Keywords: | lipid peroxidation endothelial cell monocyte atherosclerosis |
| 本文献已被 CNKI 维普 等数据库收录！ | |