低能量激光照射治疗对肿瘤患者放化疗后口腔黏膜炎的疗效观察

目的：观察低能量激光照射治疗对肿瘤患者放化疗后口腔黏膜炎的预防作用。方法：肿瘤科放化疗患者60例，用数字随机表法随机分为实验组（n＝30）和对照组（n＝30），两组患者放化疗方案根据肿瘤科方案进行，口腔护理采用相同的标准进行，实验组进行低能量激光照射，每天1次，每周5次，对照组无低能量激光照射，两组患者分别与实验开始后1、2、3、4周由口腔医师检查患者口腔黏膜炎严重程度及疼痛程度，进行评定。结果：实验组患者口腔黏膜炎的严重程度和疼痛程度较对照组明显降低，口腔黏膜炎3级、4级发生率两组间差异均有统计学意义。结论：低能量激光照射对肿瘤患者放化疗后的口腔黏膜炎具有明显的预防作用。

Evaluation of low-level laser therapy in the prevention of chemotherapy-induced mucositis

Objective: To investigate the effect of low-level laser therapy in the prevention of radiation-induced mucositis. Method: A total of 60 tumor patients with the treatment of radiation and chemotherapy were randomly assigned to two groups. The treatment group(n=30) were used low-level laser therapy one time a day, five times a week. The control group(n=30) were without low-level laser therapy. Both the patients in the two groups with the experimental began after 1, 2, 3 and 4 weeks were assessed by professional oral physician for the serious and pain degree of oral mucositis. Result: The severity of the experimental group patients with mucositis and pain levels significantly lower than the control group. There were statistically significant difference in the incidence of mucositis level 3 and level 4, respectively. Conlusion: Low-level laser therapy has obvious effect to prevent the chemotherapy-induced mucositis of tumor patients.