轻微精神病综合征患者症状学特征及共病精神障碍状况

目的:探讨轻微精神病综合征(APS)患者症状学特征及共病精神障碍状况。方法:使用精神病风险综合结构式访谈(SIPS)对101名精神科门诊求助者进行精神病风险症状评估,对其中符合APS诊断标准者使用简明国际神经精神访谈(MINI)评估共病精神障碍情况。结果:检出28例(27.7%)求助者为APS患者,其中具有特异性风险症状"异常思维内容"或"猜疑被害观念"各21例(75%),非特异性风险症状"社交兴趣缺乏"12例(42.9%),一般症状"睡眠障碍"或"心境烦躁不安"各12例(42.9%);19例(67.9%)共病≥1种精神障碍,其中11例(39.3%)为抑郁障碍,10例(35.7%)为焦虑障碍。结论:APS患者常见的风险症状是思维障碍及社交兴趣缺乏;常共病抑郁障碍或焦虑障碍。

SymPtoms characteristics and the status of comorbid Psychiatric disorder in Patients with attenuated Psychosis syndrome

ObJective:To expore the symptoms characteristics and status of the comorbid psychiatric dis-order in patients with attenuated psychosis syndrome(APS). Method:The psychosis-risk symptoms were e-valuated using psychosis risk comprehensive structured interview(SIPS)in 101 psychological help-seeking peo-ple of psychiatric clinic;and status the comorbid psychiatric disorder for which conformed APS diagnosis stand-ard were assessed using mini-international neuropsychiatric interview(MINI). Results:Twenty-eight(27. 7% ) of the psychological help-seeking people were APS patients. The specific risk symptoms such as“ abnormal thinking content”and“suspicion murdered concept”were found each in 21 cases(75% );the non-specific risk symptoms such as“social interest lack”was found in 12 cases(42. 9% );the general symptoms such as“sleep disorder”and“mood irritability”were found each in 12 cases(42. 9% ). Nineteen cases(67. 9% )comorbid at the least one kind of psychiatric disorders,including 11 cases(39. 3% )comorbid depressive disorders,10 cases(35. 7% )comorbid anxiety disorder. Conclusion:The common psychosis-risk symptoms in APS pa-tients are thought disorder and lack of social interests;and often comorbid depression or anxiety disorders.