Formation of extracellular α-amylase by Bacillus subtilis in relation to guanosine polyphosphates

The kinetics of growth, extracellular α-amylase formation and pool sizes of guanosine polyphosphates (p)ppGpp and adenosine phosphates (ATP and AMP) were determined during discontinuous cultivation of Bacillus subtilis 44. The results indicate a positive involvement of (p)ppGpp in the regulation of the expression of the α-amylase gene.