| 正交试验优选红藤凝胶的提取工艺 |
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| 引用本文： | 寿旦,胡光涛,章建民,俞忠明.正交试验优选红藤凝胶的提取工艺[J].中国药房,2007,18(27):2109-2111. |
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| 作者姓名： | 寿旦 胡光涛 章建民 俞忠明 |
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| 作者单位： | 1. 浙江省中医药研究院,杭州市,310007
2. 解放军324医院歇台子分院,重庆市,400041 |
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| 摘 要： | 目的:优选红藤凝胶的提取工艺。方法:以芍药苷和盐酸小檗碱的含量作为考察指标,采用L9(34)正交试验考察乙醇浓度、提取次数、乙醇用量、提取时间4个因素,以确定最佳提取工艺。结果:最佳提取工艺为红藤、赤芍、黄柏、忍冬藤、败酱草等中药,加80%乙醇,加6倍量溶剂回流提取3次,每次1.5h。结论:该优化工艺操作简单,结果稳定,适用于工业生产。
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| 关 键 词： | 提取工艺 正交试验 红藤凝胶 芍药苷 小檗碱 |
| 文章编号： | 1001-0408（2007）27-2109-03 |
| 收稿时间： | 2007-01-15 |
| 修稿时间： | 2007-05-16 |
Optimization of Extraction Technology for Hongteng Liquid Suppository by Orthogonal Test |
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| SHOU Dan,HU Guangtao,ZHANG Jianmin,YU Zhongming.Optimization of Extraction Technology for Hongteng Liquid Suppository by Orthogonal Test[J].China Pharmacy,2007,18(27):2109-2111. |
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| Authors: | SHOU Dan HU Guangtao ZHANG Jianmin YU Zhongming |
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| Institution: | Zhejiang Academy of Chinese Traditional Medicine, Hangzhou 310007, China;Xietaizi Branch of No .324 Hospital of PLA, Chongqing, 400041 |
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| Abstract: | OBJECTIVE:To optimize the extraction technology of Hongteng liquid suppository.METHODS:The contents of Paeoniflorin and Berberine hydrochloride were taken as the indexes to optimize the extraction technology.4 influential factors including concentration of alcohol,frequency of extraction,the dosage of solvent and time of extraction were investigated with orthogonal test L9(34).RESULTS:The optimal extraction technique was to extract herbal medicines which consisted of Sargentgloryvine Stem,Paeoniae Radix,Cortex Phellodendri,Caulis Lonicerae and Dahurian Patrinia Herb etc with 80% alcohol at 6 times the weight of herbal material for 3 times,1.5h every time.CONCLUSION:This technology is simple,stable and suitable for industrialized production. |
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| Keywords: | Extraction technology Orthogonal test Hongteng liquid suppository Paeoniflorin Berberine |
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