| 椎间盘退变过程中软骨终板AQP3的表达变化 |
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| 引用本文： | 曹国永,杨渝勇,蒋勇,龙毅,李杰,周跃. 椎间盘退变过程中软骨终板AQP3的表达变化[J]. 重庆医学, 2011, 40(4): 359-361. DOI: 10.3969/j.issn.1671-8348.2011.04.021 |
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| 作者姓名： | 曹国永 杨渝勇 蒋勇 龙毅 李杰 周跃 |
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| 作者单位： | 曹国永,杨渝勇,蒋勇,龙毅,李杰,Cao Guoyong,Yang Yuyong,Jiang Yong,Long Yi,Li Jie(武警重庆总队医院骨科,400061);周跃,Zhou Yue(第三军医大学新桥医院骨科,重庆,400037) |
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| 摘 要： | 目的 阐明水通道蛋白3(AQP3)在椎间盘退变时表达变化特点及其与椎间盘退变的相关性.方法 建立大鼠椎间盘退变的动物模型,影像学观察模型建立的可靠性,采用RT-PCR的方法检测AQP3 mRNA表达的变化,Western blot进行AQP3蛋白的检测.结果 成功建立了大鼠椎间盘退变模型,AQP3 mRNA和蛋白的表达...
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| 关 键 词： | 椎间盘 软骨 水通道蛋白质3 |
The expression of aquaporin 3 in the progress of intervertebral discs degeneration |
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| Cao Guoyong,Yang Yuyong,Jiang Yong,Long Yi,Li Jie,Zhou Yue. The expression of aquaporin 3 in the progress of intervertebral discs degeneration[J]. Chongqing Medical Journal, 2011, 40(4): 359-361. DOI: 10.3969/j.issn.1671-8348.2011.04.021 |
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| Authors: | Cao Guoyong Yang Yuyong Jiang Yong Long Yi Li Jie Zhou Yue |
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| Affiliation: | 1.Department of Orthopaedic,Chongqing Municipal Corps Hospital,Chinese People′s Armed Police Forces,Chongqing 400061,China;2.Department of Orthopaedic,Xinqiao Hospital,Third Military Medical University,Chongqing 400061,China) |
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| Abstract: | Objective To elucidate the expression characteristics of aquaporin 3(AQP3) in the intervertebral discs degeneration,and the correlation between the expression and intervertebral disc degeneration.Methods The animal model of lumbar intervertebral discs degeneration was constructed by destroying the balance of lumbar stabilization.The expression of AQP3 was detected by RT-PCR and Western blot.Results By lumbar disequilibrium,the rattus model of lumbar intervertebral discs degeneration was set up.Following the... |
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| Keywords: | intervertebral disk cartilage aquaporin 3 |
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