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溶血磷脂酸、氧化型低密度脂蛋白与不同类型脑梗死的关系
引用本文:李世英,刘美香,夏静. 溶血磷脂酸、氧化型低密度脂蛋白与不同类型脑梗死的关系[J]. 重庆医学, 2011, 40(2). DOI: 10.3969/j.issn.1671-8348.2011.02.009
作者姓名:李世英  刘美香  夏静
作者单位:华北煤炭医学院附属医院神经内科,河北唐山,063000
摘    要:
目的 通过测定不同类型急性脑梗死患者血浆中的溶血磷脂酸(LPA)、氧化型低密度脂蛋白(ox-LDL)水平,探索两者与不同临床类型脑梗死的关系.方法 选择发病3 d以内的急性脑梗死患者123例,分为初发性与复发性脑梗死组,进展性与非进展性脑梗死组,轻、中、重型脑梗死组.选择同期住院的非缺血性脑血管病患者50例为对照组.所有研究对象均采用改良的无机磷定量方法 测定LPA,ELISA法测定ox-LDL.结果 LPA、ox-LDL水平脑梗死组高于对照组,复发组高于初发组,进展组高于非进展组,重型组高于轻型组,差异均有统计学意义(P<0.05).结论 急性脑梗死患者LPA、ox-LDL水平增高,与脑梗死的发生、进展及严重程度相关.

关 键 词:脑梗死  溶血磷脂素类  脂蛋白类,LDL

Association between lysophosphatidic acid,oxidized lowdensity lipoprotein and subtypes of cerebral infarction
Li Shiying,Liu Meixiang,Xia Jing. Association between lysophosphatidic acid,oxidized lowdensity lipoprotein and subtypes of cerebral infarction[J]. Chongqing Medical Journal, 2011, 40(2). DOI: 10.3969/j.issn.1671-8348.2011.02.009
Authors:Li Shiying  Liu Meixiang  Xia Jing
Affiliation:Li Shiying,Liu Meixiang,Xia Jing(The Department of Neurology,Affiliated Hospital of North China Coal Medical College,Tangshan,Hebei 063000,China)
Abstract:
Objective To investigate the relationship between the concentration of lysophosphatidic acid(LPA) and oxidized lowdensity lipoprotein(ox-LDL) in blood and subtypes of cerebral infarction(CI).Methods One hundred and twenty-three patients who were diagnosed as CI within 3 days after the attack.All the patients were divided into subgroups:once and once more CI,progressive and non-progressive CI,light,medium and severe CI.At the same time 50 patients who without ischemic cerebrovascular disease were selected as...
Keywords:brain infarction  lysophospholipids  lipoproteins  LDL  
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