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食管癌组织MRP1/CD9的表达及临床意义
引用本文:季润元,沈阳,王成海,孙泽,冯振卿. 食管癌组织MRP1/CD9的表达及临床意义[J]. 中国肿瘤, 2004, 13(12): 812-813
作者姓名:季润元  沈阳  王成海  孙泽  冯振卿
作者单位:1. 江苏省淮阴卫生学校,江苏,淮安,223300
2. 江苏省淮安市第二人民医院,江苏,淮安,223302
3. 扬州大学医学院,江苏,扬州,225001
4. 江苏省泗洪县分金亭医院,江苏,泗洪,223600
5. 南京医科大学病理学系,江苏,南京,210029
摘    要:
[目的]探讨食管癌组织中MRP1/CD9表达的临床意义.[方法]应用免疫组化SABC法,检测54例食管癌组织中MRP1/CD9的表达.[结果]无淋巴结转移的食管癌组织和有淋巴结转移的食管癌组织MRP1/CD9阳性表达率分别为68.4%(26/38)、31.3%(5/16).食管癌组织MRP1/CD9的表达与淋巴结转移、肿瘤的分级、术后存活时间显著相关(P<0.05).[结论]MRP1/CD9可作为食管癌的预后指标.

关 键 词:食管肿瘤  免疫组织化学
文章编号:1004-0242(2004)12-0812-02

The Expression and Clinical Significance of Motility-related Protein(MRP1/CD9)in Esophageal Cancer
I Run-yuan,SHEN Yang,WANG Cheng-hai,et al.. The Expression and Clinical Significance of Motility-related Protein(MRP1/CD9)in Esophageal Cancer[J]. CHINA CANCER, 2004, 13(12): 812-813
Authors:I Run-yuan  SHEN Yang  WANG Cheng-hai  et al.
Affiliation:I Run-yuan1,SHEN Yang2,WANG Cheng-hai3,et al.
Abstract:
To investigate the expression of motility-related protein 1(MRP1/CD9) in esophageal cancer tissues and its clinical significance.The expression of MRP1/CD9 in esophageal cancer tissues was assayed by SABC immunohistochemical method in 54 cases.The expression of MRP-1/CD9 in esophageal cancer tissue in patient without and with lymph node metastasis was 68.4%(26/38)and 31.3%(5/16)respectively.The expression of MRP-1/CD9 correlated with lymph node metastasis,tumor differentiation,and postoperative survival(P<0.05).[Conclusion]MRP1/CD9 is a prognostic index for esophageal cancer.
Keywords:MRP1/CD9
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