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注射用七叶皂苷钠中七叶皂苷钠A和B的含量测定
引用本文:沈芊,曾艳,王淑洁,王育琴. 注射用七叶皂苷钠中七叶皂苷钠A和B的含量测定[J]. 中成药, 2004, 26(4): 286-288
作者姓名:沈芊  曾艳  王淑洁  王育琴
作者单位:首都医科大学宣武医院药剂科,北京,100053
摘    要:
目的:对北京市场上的注射用七叶皂苷钠进行含量测定,为控制产品质量提供依据.方法:依据国家标准,采用酸碱中和滴定法测定注射用七叶皂苷钠中总皂苷含量,同时采用高效液相色谱法测定七叶皂苷钠A和七叶皂苷钠B的含量.结果:不同厂家的样品中总皂苷含量均符合国家标准规定;而七叶皂苷钠A和七叶皂苷钠B的含量存在差别.结论:国家标准实施后,注射用七叶皂苷钠产品中七叶皂苷钠A和七叶皂苷钠B的含量有较大提高.

关 键 词:七叶皂苷钠
文章编号:1001-1528(2004)04-0286-03

Comparative study on quality of Sodium Aescinate for injection of different manufacturer
SHEN Qian,ZENG Yan,WANG Shu jie,WANG Yu qin. Comparative study on quality of Sodium Aescinate for injection of different manufacturer[J]. Chinese Traditional Patent Medicine, 2004, 26(4): 286-288
Authors:SHEN Qian  ZENG Yan  WANG Shu jie  WANG Yu qin
Abstract:
AIM: To determine the contents of Sodum Aescinate for Injection in Beijing market in order to provide the basis for quanlity control. METHODS: According to national criterion, total aescinate is determinted by acid base titration. The contents of sodium aescinate A and sodium aescinate B in products are determined by HPLC. RESULTS: The total aescinate content in samples of the different manufactures are accord with national criterion, but the contents of sodium aescinate A and sodium aescinate B in products are different. CONCLUSION: After national criterion was carried into practice, the contents of sodium aescinate A and sodium aescinate B in products were up to standard.
Keywords:HPLC
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