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Consenso de expertos sobre propuestas para la mejora del manejo de la dislipemia aterogénica
Authors:Jesú  s Millá  n Nú  ñ  ez-Corté  s,Juan Pedro-Botet,Á  ngel Brea-Hernando,Á  ngel Dí  az-Rodrí  guez,Pedro Gonzá  lez-Santos,Antonio Herná  ndez-Mijares,Teresa Mantilla-Morató  ,Xavier Pintó  -Sala,Rafael Simó  
Affiliation:1. Servicio de Medicina Interna, Hospital Universitario Gregorio Marañón, Universidad Complutense de Madrid, Madrid, España;2. Unidad de Lípidos, Hospital del Mar, Universitat Autònoma de Barcelona, Barcelona, España;3. Servicio de Medicina Interna, Hospital San Pedro, Logroño, La Rioja, España;4. Centro de Salud de Bembibre, Bembibre, León, España;5. Servicio de Medicina Interna, Hospital Universitario Virgen de la Victoria, Universidad de Málaga, Málaga, España;6. Servicio de Endocrinología, Hospital Universitario Dr. Peset, Universitat de València, Valencia, España;g Centro de Salud Prosperidad, Madrid, España;h Servicio de Medicina Interna, Hospital de Bellvitge, Universidad de Barcelona, L’Hospitalet de Llobregat, Barcelona, España;i Institut de Recerca Vall d’Hebron, Universitat Autònoma de Barcelona, Barcelona, España
Abstract:

Introduction and objectives

Although atherogenic dyslipidemia is a recognized cardiovascular risk factor, it is often underassessed and thus undertreated and poorly controlled in clinical practice. The objective of this study was to reach a multidisciplinary consensus for the establishment of a set of clinical recommendations on atherogenic dyslipidemia to optimize its prevention, early detection, diagnostic evaluation, therapeutic approach, and follow-up.

Methods

After a review of the scientific evidence, a scientific committee formulated 87 recommendations related to atherogenic dyslipidemia, which were grouped into 5 subject areas: general concepts (10 items), impact and epidemiology (4 items), cardiovascular risk (32 items), detection and diagnosis (19 items), and treatment (22 items). A 2-round modified Delphi method was conducted to compare the opinions of a panel of 65 specialists in cardiology (23%), endocrinology (24.6%), family medicine (27.7%), and internal medicine (24.6%) on these issues.

Results

After the first round, the panel reached consensus on 65 of the 87 items discussed, and agreed on 76 items by the end of the second round. Insufficient consensus was reached on 3 items related to the detection and diagnosis of atherogenic dyslipidemia and 3 items related to the therapeutic goals to be achieved in these patients.

Conclusions

The external assessment conducted by experts on atherogenic dyslipidemia showed a high level of professional agreement with the proposed clinical recommendations. These recommendations represent a useful tool for improving the clinical management of patients with atherogenic dyslipidemia. A detailed analysis of the current scientific evidence is required for those statements that eluded consensus.Full English text available from:www.revespcardiol.org/en
Keywords:cHDL, colesterol unido a lipoproteí  nas de alta densidad   cLDL, colesterol unido a lipoproteí  nas de baja densidad
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