重症肺炎患儿血小板计数监测及其与预后的关系

目的探讨重症肺炎患儿血小板计数变化及其与预后的关系。方法收集崇州市人民医院儿科住院治疗的重症肺炎患儿50例，根据患儿的预后分为两组：好转组32例和恶化组18例。分别在入院后第1、2、3、4、5d进行血小板计数监测，分析血小板计数与预后的关系。结果好转组和恶化组患儿入院第1d的血小板计数之间比较，差异无统计学意义（P〉0．05），好转组入院后第2、3d的血小板计数显著下降，之后维持稳定状态；而恶化组患儿从入院后第2d起，血小板计数呈持续下降趋势，两组间比较差异有统计学意义（P〈0．05）。结论动态监测血小板的变化对判断重症肺炎患儿预后具有重要的预警价值，可作为评估患儿预后的一个比较可靠的监测指标。

Relationship Between the Platelet Counts and the Prognosis of Severe Pneumonia in Children

Objective To study the changes of platelet counts and the relation between the platelet counts and the prognosis of severe pneumonia in children.Methods Fifty children with severe pneumonia hospitalized in the People’s Hospital of Chongzhou were enrolled in this study.According to the prognosis,50 cases were divided into clinical improvement group(n=32) and aggravated group(n=18).The platelet counts were measured at the 1st,2nd,3rd,4th,and 5th days after admission and the correlation between platelet counts and the prognosis were analyzed.Results No statistically significant difference was found in the platelet counts at the first day after admission between clinical improvement group and aggravated group(P>0.05).The level of platelet in clinical improvement group decreased significantly at the 2nd and 3rd days after admission,and then kept the level steadily.The level of platelet in aggravated group decreased continuously from the second day after admission.There were statistically significant differences in the level of platelet between the two groups(P<0.05).Conclusions Dynamically monitoring the variation of the platelet count is of great predictive value for judging the prognosis of severe pneumonia in children.It can be considered as a reliable monitoring indicator for assessing the prognosis.