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应激性高血糖对急性心肌梗死患者冠脉病变程度及心功能的影响
引用本文:邢丽娜,王志荣,刘宗军,金惠根,丘洪.应激性高血糖对急性心肌梗死患者冠脉病变程度及心功能的影响[J].实用预防医学,2012,19(2):234-236.
作者姓名:邢丽娜  王志荣  刘宗军  金惠根  丘洪
作者单位:1. 同济大学医学院,上海 200092;上海中医药大学附属普陀医院,上海 200092
2. 同济大学附属同济医院,上海,200092
3. 上海中医药大学附属普陀医院,上海,200092
摘    要:目的探讨应激性高血糖对急性心肌梗死患者冠脉病变程度及心功能的影响。方法对106例急性心肌梗死入院的患者根据空腹或即刻血糖、糖化血清蛋白、糖化血红蛋白指标进行分组,分成血糖正常组(A组,38例)、应激性高血糖组(B组,33例)和糖尿病组(C组,35例),并对三组患者的血脂指标、C反应蛋白、左室射血分数以及冠脉积分进行对比分析。结果应激性高血糖组(B组)和糖尿病组(C组)与血糖正常组(A组)相比左室射血分数显著降低,冠脉积分显著增高(P<0.05),C反应蛋白也显著增高(P<0.01),B、C两组差异无统计学意义(P>0.05)。结论应激性高血糖可加重冠脉病变程度,使急性心肌梗死患者心功能下降。

关 键 词:急性心肌梗死  应激性高血糖  心功能

Effect of Stress Hyperglycemia on Degree of Coronary Artery Affection and Cardiac Function of Acute Myocardial Infarction Patients
Institution:XING Li-na,WANG Zhi-rong,LIU Zong-jun,et al.(The Medical School of Tongji University,Shanghai 200092,China)
Abstract:Objective To explore the effect of stress hyperglycemia on the coronary artery disease and the cardiac function of acute myocardial infarction patients. Methods According to empty stomach or instantly serum glucose,saccharifying serum protein,and glycosylated hemoglobin,106 patients with acute myocardial infarction were divided into euglycemia group(group A,n=38),stress hyperglycemia group(group B,n=33),and diabetes group(group C,n=35).And the blood-fat,CRP,left ventricular ejection fraction(LVEF),the score of coronary artery in the patients were analyzed among the three groups. Results The LVEF of group B and C was lower but the score of coronary artery and CRP were higher than those of group A(P<0.05,P<0.01).No statistically significant difference was found between groups B and C(P>0.05). Conclusions Stress hyperglycemia may aggravate the degree of coronary artery disease and lower the cardiac function of acute myocardial infarction patients.
Keywords:Acute myocardial infarction  Stress hyperglycemia  Cardiac function
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