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| ~(131)I-CEA M cAb免疫显像诊断卵巢癌的初步研究 | |
| 引用本文： | 胡立宽,贾士铨,谢天豪,韩建奎,康福,刘清太. ~(131)I-CEA M cAb免疫显像诊断卵巢癌的初步研究[J]. 山东大学学报(医学版), 1988, 0(4) |
| 作者姓名： | 胡立宽 贾士铨 谢天豪 韩建奎 康福 刘清太 |
| 作者单位： | 山东医科大学核医学教研室(胡立宽，贾士铨，谢天豪，韩建奎，康福)，山东医科大学核医学教研室(刘清太) |
| 摘 要： | 用~(131)I-CEA McAb放射免疫显像诊断10例卵巢癌患者,使用γ-闪烁显像辅以微机图像处理技术和双核素减影术获得较好效果。10例全部阳性显像,与手术及病理结果完全相符,卵巢癌RII分期与手术分期亦完全符合。31处转移灶发现30处,阳性率97%,最小检出病灶直径1.5cm。本法在对病灶进行定性诊断同时可直接显示病灶位置、形态、大小及数量。对早期发现、指导临床分期、估计预后有较高的临床价值。 |
| 关 键 词： | 卵巢肿瘤 放射免疫显像 抗体 单克隆 癌胚抗原 |
A PRELIMINARY STUDY OF RADIOIMMUNOIMAGING OF OVARIAN MALIGNANCY WITH I-131 LABELLED CEA MONOCLONAL ANTIBODY |
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| Hu Likuan et al Dept.of Nucl.Med.,Shandong Medical University. A PRELIMINARY STUDY OF RADIOIMMUNOIMAGING OF OVARIAN MALIGNANCY WITH I-131 LABELLED CEA MONOCLONAL ANTIBODY[J]. Journal of Shandong University:Health Sciences, 1988, 0(4) | |
| Authors: | Hu Likuan et al Dept.of Nucl.Med. Shandong Medical University |
| Abstract: | Ten cases of ovarian cancers have been detected with I 131 labelled CEA McAb and computer assisted clual radionuclide subtraction tech-nique.The lesions(both primary and secondary)are clearly visualized andproved by surgical and pathohistological findings.30 of 31 metastatic lesionsare localized with a positive rate 97%.It seems to be a sensitive andspecific procedure for early diagnosis of ovarian cancer so far.It is alsovaluable for staging clinical course and making decision on treatment,assessing the prognosis of ovarian cancer as well. |
| Keywords: | Ovarian neoplasms Radioimmunoimaging Antibodies monoclonal Carcinoembry onic antigen |
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