| 肾虚证相关基因的研究 |
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| 引用本文： | 赵晓山,罗仁. 肾虚证相关基因的研究[J]. 中西医结合学报, 2003, 1(1): 18-20 |
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| 作者姓名： | 赵晓山 罗仁 |
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| 作者单位： | 第一军医大学南方医院中医科,广东,广州,510515 |
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| 基金项目： | 国家自然科学基金资助项目 (3 0 2 715 73 ) |
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| 摘 要： | 本文提出研究肾虚证的相关基因可以从单一病证入手，应用基因芯片、RDA方法、基因序列分析等现代分子生物学技术筛选肾虚证患者的差异基因，最后研究这些基因与肾虚证表型的内在联系，只有证实某些基因能对肾虚证的病理生理状态施加影响，才可确定此基因是肾虚证的相关基因。此研究思路与方法还可用于其他中医证候相关基因的研究。
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| 关 键 词： | 肾虚证 基因 分子生物学 生物技术 克隆 |
| 文章编号： | 1672-1977(2003)01-0018-03 |
| 修稿时间： | 2003-01-29 |
Study of genes related with kidney deficiency syndrome |
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| ZHAO Xiao Shan,LUO Ren. Study of genes related with kidney deficiency syndrome[J]. Journal of Chinese integrative medicine, 2003, 1(1): 18-20 |
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| Authors: | ZHAO Xiao Shan LUO Ren |
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| Affiliation: | Department of Traditional Chinese Medicine, Nanfang Hospital, First Military Medical University, Guangzhou, Guangdong Province 510515, China. zhangxq@fimmu.com |
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| Abstract: | Study of kidney deficiency syndrome may utilize the modern molecular biology technique, such as gene chip, representational difference analysis (RDA) and genes sequence analysis, to clone the different genes of kidney deficiency syndrome from single TCM syndrome type of the disease, to investigate the inner connection between the various phenotypes of kidney deficiency syndrome and their genes expression pattern and their function products, then to definite the related genes of kidney deficiency syndrome. The research method may also be used for the study of other TCM syndrome types. |
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| Keywords: | biotechnology kidney deficiency syndrome gene cloning |
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