食物不耐受检测在儿童哮喘中的临床意义

目的研究食物不耐受检测在儿童哮喘中的临床意义。方法我院门诊及住院确诊的哮喘患儿106例作为观察组，非哮喘但有肺炎或腹泻的门诊儿童71例作为对照组。所有患儿血清ELISA方法检测14种食物的IgG抗体，设置〈50U／mL为阴性，〉50U／mL为阳性，进行统计学分析。结果观察组食物不耐受率为95．3％，而对照组仅为31％，两组比较差异有统计学意义（P〈0．05））。不耐受食物分布高低依次为：鸡蛋、牛奶、虾、蟹、鸡肉、牛肉、大豆、玉米、鱼、小麦、大米、西红柿、猪肉、蘑菇。食物不耐受与食物、呼吸过敏原检测比较在两种检测中完全一致的占66．0％（70／106），不一致的占34％（36／106），食物、呼吸过敏检测阴性的34例中，食物不耐受阳性32．1％，差异有统计学意义（P〈0．05）。结论食物不耐受作为食物、呼吸过敏原检测的有力补充，在儿童哮喘方面的诊断治疗中起到了重要作用，对哮喘患儿的饮食情况有更加全面的指导意义。

Clinical significance of detection of food intolerance in childhood asthma

Objective To study the clinical significance of detection of Food Intolerance in Chilhood Asthma.Methods 106 cases of children diagnosed as asthma from pediatric in and out patient departments of Hospital as observation group,71 cases of children diagnosed pneumonia or diarrhea in outpatient children as control group.IgG antibodies of 14 kinds of food were detected by ELISA(<50U/mL was negative,>50U/mL was positive).Data was analysed.Results Food intolerance rate was 95.3% in observation group,while the control group only 31%,there was statistically significant difference(P < 0.05).The positive rate of food intolerance antibody IgG declined as following:eggs,milk,shrimp,crab,chicken,beef,soybeans,corn,fish,wheat,rice,tomatoes,pork,mushrooms.Only 66.0%(70/106) showed the same results in these two tests,34%(36/106) of them presented different outcome.It was negative in food and respiratory allergen test,but 32.1% individuals in different result presented positive in the food intolerance detection.There was statistically significant(P < 0.05).Conclusion Food intolerance as a strong complement for food and respiratory allergen detection,and played an important role in the diagnosis and treatment of childhood asthma,more comprehensive guidance on the diet of children with asthma.