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白细胞介素-2联合顺铂治疗恶性胸腔积液的疗效观察
引用本文:杨茁,任亚娟,徐灵彬.白细胞介素-2联合顺铂治疗恶性胸腔积液的疗效观察[J].现代肿瘤医学,2007,15(11):1605-1607.
作者姓名:杨茁  任亚娟  徐灵彬
作者单位:陕西省人民医院干4科,陕西,西安,710068
摘    要:目的:观察白细胞介素-2(rhIL-2)联合顺铂治疗恶性胸腔积液的临床疗效。方法:44例恶性胸腔积液患者随机分为治疗组和对照组,抽尽胸液之后,治疗组胸腔注入白细胞介素-2 顺铂,每周1次,1~3周为1疗程,4周后观察疗效。结果:治疗组总有效率为82.61%,对照组总有效率52.38%,两组比较差异有显著性(P<0.05)。结论:白细胞介素-2联合顺铂治疗恶性胸腔积液疗效满意,值得临床推广。

关 键 词:恶性胸腔积液  白细胞介素-2  顺铂
文章编号:1672-4992-(2007)11-1605-03
修稿时间:2007-01-31

Treatment of malignant pleural effusion by rhIL-2 combined with cisplatin
YANG Zhuo,REN Ya-juan,XU Ling-bin.Treatment of malignant pleural effusion by rhIL-2 combined with cisplatin[J].Journal of Modern Oncology,2007,15(11):1605-1607.
Authors:YANG Zhuo  REN Ya-juan  XU Ling-bin
Institution:Shaanxi Provincial People Hospital, xian 710068 ,China.
Abstract:Objective:To observe the clinical effect of rhIL-2 combined with cisplatin in treating malignant pleural effusion.Methods:Total of 44 cases were randomly divided into treatment group and control group.First withdraw all the pleural effusion,after that the treatment group was injected rhIL-2 and cisplatin,control group was injected cisplatin once a week,1~3 weeks for one course,4 weeks later,observe the effect.Results:Total effective rate of treatment group was 82.6%,that of control group 52.38%,there was obvious difference between them(P<0.05).Conclusion:rhIL-2 combined with cisplatin is effective in treating malignant pleural effusion.
Keywords:malignant pleural effusion  recombinate human interleukin-2(rhIL-2)  cisplatin
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