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巩膜腔内异种异体骨移植的临床应用研究
引用本文:郑世英,孙小玲,刘剑萍,许呜,赵汉池,余永红,聂尚武,张斌,王晓琴,周先略.巩膜腔内异种异体骨移植的临床应用研究[J].中华医学美学美容杂志,1996(3).
作者姓名:郑世英  孙小玲  刘剑萍  许呜  赵汉池  余永红  聂尚武  张斌  王晓琴  周先略
作者单位:湖北省荆沙市中心医院
摘    要:作者为探索一种理想的生物材料植入巩膜腔内,用以防治眼内容物剜除术后的继发畸形。在动物实验的基础上,于临床行眼内容物剜除术后将部分脱蛋白猪骨和脱钙同种异体骨碎块各1.5克混合移植于巩膜腔内,4周后安装义眼。24例均无排斥反应及交感性眼炎发生,双眼外观对称,义眼活动满意。1个月后X线片显示有新骨生成现象,半年后复合骨由新骨替代,2年后随访,疗效稳定。认为本复合骨移植作为眼内充填物具有对人体无害,质轻,机械强度高,骨诱导能力和组织相容性良好等优点

关 键 词:巩膜腔  部分脱蛋白猪骨  脱钙同种异体骨

Cliniealresearchonthetransplantationofthebiologicalcompoundboneintothescleralcavity
ZhengShiying,Sunxiaolin,LiuJianping,et al..Cliniealresearchonthetransplantationofthebiologicalcompoundboneintothescleralcavity[J].Chinese Journal of Medical Aesthetics and Cosmetology,1996(3).
Authors:ZhengShiying  Sunxiaolin  LiuJianping  
Institution:ZhengShiying,Sunxiaolin,LiuJianping,etal.TheCentreHospitalofJingshaCity,Hubei434100
Abstract:Wesoughtforanidealbiologicalmaterialwhichcanbetransplantedintoscleralcavityinordertopreventandcureorbitalsecondarydeformityaftereviscerationofeye.Basedontheanimalex-perimentstudy,themixtureofbonegraft(1.5gramsofdeproteinprocinebonepiecesand1.5gramsofdecalcifyinghomoplasticbonepieces)wastransplantedintotheautogenousscleralcavityaftereviscera-tionofeye.Fourweekslater,theartificialeyeswereinserted.Therewerenorejectreactionandsympa-theticophthalmiainal24cases.Theoutwardappearanceandmovementoftheartificialeyesweresatis-fiedalso.Onemonthlater,thex-raypictureshowedthegrowthofthenewbone.Aftersixmonthes,thecompoundbonewasreplacedbythenewbone.Intwo-yearfolow-upsuney,itimprovedthatthetreatmentefectwasstable.Theconclusionconfirmedthatthecompoundboneasthegraftmaterialhasnoside-effect.lightweightenoughmachanicalstrength.goodrevulsivecapacityandtissuecompatibilityadvantages.
Keywords:ScleralcavityPartialdeproteinprocineboneDecalcifyinghomoplasticbone
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