Comparison of topical antibacterial agents in the preparation of varicose ulcers for skin grafting |
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Authors: | H P Henderson R R Marples J F Richardson |
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Institution: | 1. North East Thames Regional Plastic Surgery Unit, London UK;2. Central Public Health Laboratory, Colindale, London UK |
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Abstract: | The short-term effects of five topical antibacterial formulations on the microbial flora of 75 varicose ulcers were studied to develop a preparative programme for skin grafting. The flora before treatment was complex including enterobacteria, pseudomonads, streptococci and staphylococci. Chlorhexidine and gentamicin formulations significantly reduced the number of organisms within 48 h but the antibiotic failed to eliminate streptococci. |
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Keywords: | Reprint requests to: R R Marples Division of Hospital Infection Central Public Health Laboratory Colindale London NW9 SHT |
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