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Comparison of topical antibacterial agents in the preparation of varicose ulcers for skin grafting
Authors:H P Henderson  R R Marples  J F Richardson
Institution:1. North East Thames Regional Plastic Surgery Unit, London UK;2. Central Public Health Laboratory, Colindale, London UK
Abstract:The short-term effects of five topical antibacterial formulations on the microbial flora of 75 varicose ulcers were studied to develop a preparative programme for skin grafting. The flora before treatment was complex including enterobacteria, pseudomonads, streptococci and staphylococci. Chlorhexidine and gentamicin formulations significantly reduced the number of organisms within 48 h but the antibiotic failed to eliminate streptococci.
Keywords:Reprint requests to: R  R  Marples  Division of Hospital Infection  Central Public Health Laboratory  Colindale  London NW9 SHT  
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