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Curcumin mediated down‐regulation of αVβ3 integrin and up‐regulation of pyruvate dehydrogenase kinase 4 (PDK4) in Erlotinib resistant SW480 colon cancer cells
Authors:Samira Javadi  Kobra Rostamizadeh  Jalal Hejazi  Maliheh Parsa  Mojtaba Fathi
Affiliation:1. Student Research Committee, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran;2. Zanjan Pharmaceutical Nanotechnology Research Center (ZPNRC), Department of pharmaceutical Biomaterials, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran;3. Department of Biochemistry and Nutrition, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran;4. Department of Toxicology and Pharmacology, Faculty of Pharmacology, Zanjan University of Medical Sciences, Zanjan, Iran;5. Cancer Gene Therapy Research Center, Zanjan University of Medical Sciences, Zanjan, Iran
Abstract:
Keywords:colon cancer  curcumin  EGFR  erlotinib  mPEG‐PCL  PDK4  α    3 integrin
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