| 心泰胶囊(加味丹参饮)提取工艺的优选 |
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| 引用本文： | 孙永宁,陆兔林,余大强,张家铭,金能革,马建慧.心泰胶囊(加味丹参饮)提取工艺的优选[J].成都中医药大学学报,2004,27(4):50-52. |
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| 作者姓名： | 孙永宁 陆兔林 余大强 张家铭 金能革 马建慧 |
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| 作者单位： | 上海交通大学,医学院,上海,200030;南京中医药大学,江苏,南京,210029 |
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| 基金项目： | 上海市科学技术委员会自然科学基金 (0 3411994 8) |
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| 摘 要： | 目的：正交实验法优选心泰胶囊提取工艺。方法：采用L9(3)^4正交试验法，以丹参酮ⅡA，当归、砂仁、檀香挥发油，瓜蒌中有机酸的溶出量为指标分别进行挥发油提取、醇提、水提醇沉工艺优化选择，考察各因素的影响。结果：当归、砂仁、檀香的挥发油最佳提取工艺为药材加10倍量水浸泡2h后回流提取6小时；丹参醇提最佳工艺为每次加10倍量90％乙醇回流提取3次，1．5h／次；水提醇沉最佳工艺为药材每次加21倍量水，煎煮提取2次，1h／次，浓缩液醇沉至酒精含量为70％。结论：上述实验结果为心泰胶囊提取工艺的确定提供科学实验依据。
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| 关 键 词： | 心泰胶囊 提取工艺 |
| 文章编号： | 1004-0668(2004)04-0050-03 |
| 修稿时间： | 2004年8月22日 |
Application of water and ethanolic-processing to Xin-Tai Capsule |
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| SUN Yong-ling,LU Tu-lin,YU Da-qiang,ZHANG Jia-min,JIN Neng-ge,MA Jian-hui Medical colledge,Shanghai university of Communications.Application of water and ethanolic-processing to Xin-Tai Capsule[J].Journal of Chengdu University of Traditional Chinese Medicine,2004,27(4):50-52. |
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| Authors: | SUN Yong-ling LU Tu-lin YU Da-qiang ZHANG Jia-min JIN Neng-ge MA Jian-hui Medical colledge Shanghai university of Communications |
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| Abstract: | Obiective:To research the best processing method of Xin-Tai Capsule Method: L 9(3 4)orthogonal tables aredecided with three effects: water-processing, ethanolic-processing and water-processing wit athanolic precipitated. To observe the effect of each fact. Result: The best steam-processing method is boiling 6 hours with 10 times water after being put in water for 2 hours; The best ethanolic-processing method is 1.5 hours one time with 10 times 80% ethanolic;The best water-processing method is 1 hour one time with 21 times water for 2 times,and then 70% ethanolic. Conclusion :The result above can be used for mass production. |
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| Keywords: | Xin-Tai Capsule Orthogonal design |
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