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Disease latency in Creutzfeldt-Jakob disease via dural grafting: a case report
Authors:Lang C J  Heckmann J G  Querner V  Neundörfer B  Kornhuber J  Buchfelder M  Kretzschmar H A
Affiliation:(1) Neurological Hospital with Outpatient Department, Friedrich-Alexander-University at Erlangen, Germany;(2) Neurological Hospital with Outpatient Department, Ludwig-Maximilians-University at Munich, Germany;(3) Psychiatric Hospital with Outpatient Department, Friedrich-Alexander-University at Erlangen, Germany;(4) Institute of Neuropathology, Ludwig-Maximilians-University at Munich, Germany
Abstract:
The case of a 57-year old man is reported who had been operated upon for cerebellar angioblastoma more than 19 years previously. Having received a lyophilized dural patch he developed Creutzfeldt–Jakob disease of which he died 19 months later. This is the longest latency with dura-associated Creutzfeldt–Jakob disease reported so far.
Keywords:Creutzfeldt–  Jakob disease  Disease latency  Dural grafting  Iatrogenic  Prion diseases
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