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| 血清半胱氨酸蛋白酶抑制剂C与平均肾小球体积的相关性研究 | |
| 引用本文： | 张翀,韩平治,丁进芳,司玉春,王文革,田芳. 血清半胱氨酸蛋白酶抑制剂C与平均肾小球体积的相关性研究[J]. 上海医学检验杂志, 2005, 0(5) |
| 作者姓名： | 张翀 韩平治 丁进芳 司玉春 王文革 田芳 |
| 作者单位： | 甘肃省人民医院临床检验中心 甘肃兰州730000(张翀，韩平治，丁进芳，司玉春)，兰州大学第二医院肾病科 甘肃兰州730030(王文革)，解放军407医院 甘肃天水741000(田芳) |
| 摘 要： | 目的研究血清半胱氨酸蛋白酶抑制剂C(CysC)与平均肾小球体积(MGV)的相关性,以寻求对肾小球滤过率表达的理想检验指标。方法应用颗粒增强免疫透射比浊法测定31例不同肾脏疾病肾活检患者的血清CysC浓度,同时用体视学方法测定MGV。结果CysC与MGV明显相关(r=0.715,P<0.01),与内生肌酐清除率(Ccr)显著相关(r=-0.819,P<0.01);Ccr与MGV也明显相关(r=-0.609,P<0.01);血肌酐(Cr)与MGV之间的r为0.546(P<0.05)。结论血清CysC与MGV的改变明显相关。 |
| 关 键 词： | 半胱氨酸蛋白酶抑制剂C 平均肾小球体积 内生肌酐清除率 |
Study on the correlation between serum cystatin C and mean glomerular volume |
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| ZHANG Chong,HAN Pingzhi,DING Jinfang,SI Yuchun,WANG Wenge,TIAN Fang. Centre of Clinical Laboratory,People's Hospital of Gansu Province,Gansu Lanzhou ,China. Study on the correlation between serum cystatin C and mean glomerular volume[J]. Shanghai Journal of Medical Laboratory Sciences, 2005, 0(5) | |
| Authors: | ZHANG Chong HAN Pingzhi DING Jinfang SI Yuchun WANG Wenge TIAN Fang. Centre of Clinical Laboratory People's Hospital of Gansu Province Gansu Lanzhou China |
| Affiliation: | ZHANG Chong,HAN Pingzhi,DING Jinfang,SI Yuchun,WANG Wenge,TIAN Fang. Centre of Clinical Laboratory,People's Hospital of Gansu Province,Gansu Lanzhou 730000,China |
| Abstract: | Objective To study the correlation between serum cystatin C(Cys C) and mean glomerular volume(MGV),and seek for an ideal test marker of glomerular filtration rate. Methods Serum Cys C of 31 patients with different renal disease was determined by particle-enhanced immunoturbidimetry method, MGV was measured by stereologic method. Results The level of serum Cys C was well correlated with MGV(r=(0.715),P<(0.01)) and creatinine clearance rate ((Ccr)(r=(-0.819),P<(0.01)).The correlation of (Ccr) and MGV was also good(r=(-0.609),P<(0.01)). The r value of serum creatinine and MGV was r=(0.546)(P<(0.05). Conclusions There was very good correlation between Cys C and MGV. |
| Keywords: | Cystatin C Mean glomerular volume Creatinine clearance rate |
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