纤维蛋白原活性测定在血液流变学检测中的作用及意义

目的：研究血浆中纤维蛋白原活性对血液流变性的影响。方法：对临床３７９例患者进行血浆和血清粘度的测定，应用其结果计算出纤维蛋白原的活性，按照公式：纤维蛋白原活性（ｇ／Ｌ）＝纤维蛋白原量（ｇ／Ｌ）／［血浆粘度（ｍＰａ·ｓ）－血清粘度（ｍＰａ·ｓ）］。结果：结果显示，只有在纤维蛋白原活性增强时，血浆粘度才有所提高，从而使全血粘度升高，故此纤维蛋白原活性与其含量的增粘作用不成比例。结论：临床测定纤维蛋白原活性能提高血液流变学检查的特异性及敏感性。

Effect of Hemorheologic Property on Activity of Fibrinogen in Plasma

bjective: To measure the activity of fibrinogen which is for the effect of hemorheologic property. Method: 379 cases of patient were measured for the viscosity of plasma and serum, which was used to count the activity of fibrinogen, according to the formunla: activity of fibrinogen(g/L)=quantity of fibrinogen(g/L)/Plasma viscosity(mPa·s)-serum viscosity(mPa·s)]. Result: On the strength of the fibrinogen activity only that is to increase the viscosity of plasma and then the whole blood viscosity was increased. Therefore, this can not be a proportion between the quantity and activity of fibrinogen in the function of increasing viscosity. Conclusion: To measure the activity of fibrinogen which is to rise the specific property and sensitivity for hemorheologic examination in clinic.