| 肝细胞生长因子研究进展 |
| |
| 引用本文： | 张武,陈文杰. 肝细胞生长因子研究进展[J]. 免疫学杂志, 2001, 17(Z1): 125-128 |
| |
| 作者姓名： | 张武 陈文杰 |
| |
| 作者单位： | 重庆市沙坪坝区人民医院门诊部, |
| |
| 摘 要： | 查阅近二十年国外有关HGF/SF文献,基本弄清了HGF/SF的分子结构及组织分布,说明了HGF/SF的调节和cmet受体及两者的关系,揭示了HGF/SF的生物活性、HGF/SF和肿瘤扩散以及与肝再生的关系.因此,HGF/SF在肝再生中起主要作用;是肾再生的关键因子;可促进伤口愈合;通过增加恶性细胞的侵袭性,HGF/SF可能作为肿瘤转移的重要因素之一.
|
| 关 键 词： | 肝细胞生长因子 肝再生 肾再生 肿瘤转移 |
| 文章编号： | 1000-8861(2001)03(S)-0125-04 |
| 修稿时间： | 2000-11-13 |
Progress of research on HGF/SF |
| |
| ZHANG Wu. Progress of research on HGF/SF[J]. Immunological Journal, 2001, 17(Z1): 125-128 |
| |
| Authors: | ZHANG Wu |
| |
| Abstract: | Based on the documents on HGF/SF published abroad in last two decades, we have made clear the molecular structure of HGF/SF and its distribution in tissue. In this paper, we are trying to review the regulating function of HGF/SF and its receptor c met and the relationship between HGF/SF and c met, and also to reveal its biological activity and the relationship between HGF/SF, cancer progression and liver regeneration. We have come to the following conclusions: HGF/SF plays an important role in liver regeneration; is a key factor in kidney regeneration. It can promote healing of wounds; It may also be a significant factor that induces cancer transferring through raising the chances for vicious cells to invade live organisms. |
| |
| Keywords: | HGF/SF liver regeneration kidney regeneration cancer transferring |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
