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不同年龄抑郁症患者瞬目反射的研究
引用本文:张承洁,袁勇贵,梅刚. 不同年龄抑郁症患者瞬目反射的研究[J]. 临床神经电生理学杂志, 2007, 16(5): 290-292
作者姓名:张承洁  袁勇贵  梅刚
作者单位:南京医科大学附属脑科医院,江苏南京,210029
基金项目:南京市医学科技发展项目资金资助(YKK0351)
摘    要:目的:探讨抑郁症与瞬目反射(BR)的关系。方法:对90例抑郁症(青年和老年各45例)患者及60例正常对照组(青年和老年各30例)进行BR检测。结果:与青年对照组和老年对照组比较,青年抑郁症患者和老年抑郁症患者BR的R2、R2′潜伏期分别显著延长(P<0.001),老年抑郁症患者的波幅与老年对照组、青年抑郁症患者的波幅相比显著升高,差异存在极显著意义(P<0.001)。结论:抑郁症患者存在BR的异常,提示抑郁症患者可能存在脑干功能障碍。

关 键 词:抑郁症  青年  老年  瞬目反射
文章编号:1009-5934(2007)-05-290-03
收稿时间:2007-06-01
修稿时间:2007-06-01

The study of blink reflex in patients of different ages with major depression
ZHANG Chengjie,YUAN Yonggui,MEI Gang. The study of blink reflex in patients of different ages with major depression[J]. Journal of Clinical Electroneurophysiology, 2007, 16(5): 290-292
Authors:ZHANG Chengjie  YUAN Yonggui  MEI Gang
Abstract:Objective:To evaluate the relationship between major depression and blink reflex(BR). Methods:Blink reflex were measured in 90 patients with major depression and 60 healthy volunteers.Re- suits:The latency of R2 and R2'were significantly lengthened in young depression(YD)and older depres- sion(OD)than those in young controls(YC)and old controls(OC)respectively(P<0.001);The ampli- tude of R2 and R2'in the patients with major depression was statistically higher than those of YD and OD respectively(P<0.001).Conclusions:There is abnormity of blink reflex in the patients with major de- pression,and it should be denoted that there is functionary disorder in the brain stem in old patients with depression.
Keywords:Major depression  Young  Older  Blink reflex(BR)
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