Assignment of the genes for triose phosphate isomerase to chromosome 6 and tripeptidase-1 to chromosome 10 inMus musculus by somatic cell hybridization |
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| Authors: | Leslie A. Leinwand Christine A. Kozak Frank H. Ruddle |
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| Affiliation: | (1) Department of Biology, Yale University, 06520 New Haven, Connecticut;(2) National Institute for Allergies and Infectious Diseases, National Institutes of Health, 20014 Bethesda, Maryland |
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| Abstract: | ![]()
Evidence is presented for the assignment of the gene for triose phosphate isomerase toMus musculus chromosome 6 and tripeptidase-1 to chromosome 10 by synteny testing and chromosome assignment in Chinese hamster x mouse somatic cell hybrid clones. Neither TPI nor TRIP-1 were expressed concordantly with any known isozyme markers in 45 hybrid clones (13 primary and 32 secondary). Karyotypic analysis of 21 clones showed that the expression of TPI and chromosome 6 were concordant in all cases as was expressed of TRIP-1 and chromosome 10. Both chromosomes were previously unmarked by isozymes. |
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