| 针灸对衰老模型小鼠皮肤中MDA、GSH-Px和Hyp影响的实验研究 |
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| 引用本文： | �Ӣ,���,����ũ. 针灸对衰老模型小鼠皮肤中MDA、GSH-Px和Hyp影响的实验研究[J]. 针灸推拿医学(英文版), 2011, 9(3): 142-144. DOI: 10.1007/s11726-011-0493-5 |
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| 作者姓名： | �Ӣ ��� ����ũ |
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| 作者单位： | Laboratory of Combined Acupuncture and Drugs, Nanjing University of Traditional Chinese Medicine, Jiangsu 210029,P. R. China |
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| 基金项目： | Fund Item： National Key Laboratory Cultivation of the Laboratory on Combined Acupuncture and Medication, Higher Education of Jiangsu Province |
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| 摘 要： | 目的:观察针灸对衰老模型小鼠皮肤组织形态的影响.方法:长期颈背部皮下注射D-半乳糖造成小鼠亚急性衰老模型,随机分为针刺组、艾灸组、模型组和空白组,检测皮肤组织中丙二醛(Malondialdehyde,MDA)含量、谷胱甘肽过氧化物酶(Glutathione Peroxidase,SH-Px)活力、羟脯氨酸(Hydroxyproline,Hyp)含量.结果:针灸足三里穴能够使衰老模型小鼠皮肤组织中的MDA含量减少,GSH-Px活力增强,Hyp含量增多.结论:针灸足三里穴对小鼠皮肤衰老具有拮抗作用.
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| 关 键 词： | 针灸疗法 穴,足三里 皮肤老化 丙二醛 谷胱甘肽过氧化物酶 羟脯氨酸 |
Effects of acupuncture and moxibustion on MDA, GSH-Px, and hyp in the skin of senile mice |
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| Chunying Yang,Bin Xu,Yinong Sun. Effects of acupuncture and moxibustion on MDA, GSH-Px, and hyp in the skin of senile mice[J]. Journal of Acupuncture and Tuina Science, 2011, 9(3): 142-144. DOI: 10.1007/s11726-011-0493-5 |
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| Authors: | Chunying Yang Bin Xu Yinong Sun |
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| Affiliation: | Laboratory of Combined Acupuncture and Drugs, Nanjing University of Traditional Chinese Medicine, Jiangsu 210029, P. R. China |
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| Abstract: | Objective: To observe the effects of acupuncture and moxibustion on the skin histomorphology of senile mice. Methods: The subacute senile model of mouse was made by subcutaneous injection of D-galactose into the neck, then they were randomly allocated into an acupuncture group, a moxibustion group, a model group, and a blank group, and measured the content of malondialdehyde (MDA), activity of glutathione peroxidase (GSH-Px), and content of hydroxyproline (Hyp) in the skin tissue. Results: Acupuncture and moxibustion at Zusanli (ST 36) could decrease the content of MDA, enhance the activity of GSH-Px, and increase the content of Hyp in the skin tissue of senile mice. Conclusion: Acupuncture and moxibustion at Zusanli (ST 36) could delay the senescence progress of mice's skin. |
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| Keywords: | Acupuncture-Moxibustion Therapy Points,ST 36 (Zusanli) Skin Aging Malondialdehyde Glutathione Peroxidase Hydroxyproline |
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