Clot Retraction in a Factor XIII Free System |
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| Authors: | K. Murali Krishna Rao M.D. Thomas F. Newcomb |
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| Affiliation: | Veterans Administration Hospital and the Departments of Medicine and Biochemistry, University of Florida College of Medicine, Gainesville, Florida, USA |
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| Abstract: | ![]()
The role of Factor XIII in clot retraction was studied using the plasma from Factor XIII-deficient patients. Time course experiments revealed no significant difference in clot retraction between a plasma deficient in Factor XIII and one to which purified Factor XIII had been added. Using Factor XIII-free fibrinogen and Factor XIII-deficient platelets, it is shown that there is no significant difference in clot retraction with or without added Factor XIII. |
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| Keywords: | clot retraction Factor XIII deficiency platelets |
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