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Impact of age on access site‐related outcomes in 469,983 percutaneous coronary intervention procedures: Insights from the British Cardiovascular Intervention Society
Authors:Simon G. Anderson PhD  Karim Ratib MB ChB  Phyo K. Myint MD  Bernard Keavney DM  BMBCh   BSc  Chun Shing Kwok MBBS  MSc   BSc  Azfar Zaman MD  MBChB   BSc  Peter F. Ludman MD  MA  Mark A. de Belder MD  MA  James Nolan MD  MBChB  Mamas A. Mamas DPhil  BMBCh   MA
Affiliation:1. Manchester Heart Centre, Manchester Royal Infirmary, Manchester, United Kingdom;2. Cardiovascular Research Group, Institute of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom;3. Department of Cardiology, University Hospital of North Staffordshire, Stoke‐on‐Trent, North Staffordshire, United Kingdom;4. Institute of Applied Health Sciences, School of Medicine and Dentistry, University of Aberdeen, Aberdeen, Scotland, United Kingdom;5. Department of Cardiology, Freeman Hospital, Newcastle Upon Tyne and Institute of Cellular Medicine, Newcastle University, Newcastle, United Kingdom;6. Department of Cardiology, Queen Elizabeth Hospital, Edgbaston, Birmingham, United Kingdom;7. Department of Cardiology, The James Cook University Hospital, Middlesbrough, United Kingdom;8. Farr Institute, Institute of Population Health, University of Manchester, Manchester, United Kingdom
Abstract:We investigate adoption of the TRA in different age groups and study the relationship between age and access site related outcomes in a national cohort of patients undergoing PCI in the UK. Previous studies have reported conflicting data on radial access site adoption between different age groups, with age an independent predictor of failure of procedures undertaken through the radial approach. Age and access site related outcomes (based on transradial (TRA) and transfemoral (TFA) access) were studied in 469,983 PCI procedures undertaken in the UK from 2006 to 2012 in the age groups; <60, 60–<70, 70–<80, and ≥80 in the British Cardiovascular Intervention Society database. We studied access site practice in 469,983 patients who underwent PCI procedures in the United Kingdom. TRA utilization increased from 17.5% to 65.6% in the age group <60, and 16.6% to 54.5% in the age group ≥80 between 2006 and 2012. TRA was independently associated with decreased 30‐day mortality in all age groups (<60: OR 0.64; 95% CI 0.54–0.74, P < 0.0001; 60–<70: OR 0.65; 95% CI 0.57–75, P < 0.0001, 70–<80: OR 0.58 (0.52–0.65, P < 0.0001 and ≥80: OR 0.65 (0.57–0.73, P < 0.0001). Adoption of the TRA for PCI has occurred least in older patients in the UK despite similar associations between TRA use and decreased 30‐day mortality observed in all age groups. © 2015 Wiley Periodicals, Inc.
Keywords:age  access site  outcomes  PCI
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