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Effect of prenatal antiarrhythmic treatment on cardiac function in a twin pregnancy
Authors:Van Leeuwen Peter  Schiermeier Sven  Hailer Birgit  Lange Silke  Geue Daniel  Hatzmann Wolfgang  Grönemeyer Dietrich
Affiliation:From the Department of Biomagnetism, Grönemeyer Institute of Microtherapy, University of Witten/Herdecke, Bochum, Germany;, Department of Obstetrics, Marienhospital, University of Witten/Herdecke, Witten, Germany;, Department of Internal Medicine, Philippusstift, Essen, Germany;, and Department of Radiology and Microtherapy, University of Witten/Herdecke, Bochum, Germany
Abstract:
We present a case of supraventricular tachycardia affecting one fetus in a twin pregnancy. Before and after treatment with flecainide and cardioversion, we examined conduction times and heart rate variability (HRV) in both twins on the basis of magnetocardiography. Cardiac conduction times increased in both fetuses but HRV showed opposing effects with a number of HRV measures. This case demonstrates that magnetocardiography not only enables identification of fetal arrhythmia, but also permits the investigation of the effects of antiarrhythmic treatment on the conductive system as well as on interaction with the autonomic nervous system.
Keywords:fetal arrhythmia    magnetocardiography    flecainide    cardiac time intervals    heart rate variability
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