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甘草饮片超微粉碎前后甘草酸溶出行为的比较研究
引用本文:李志猛,王跃生,李晓明,闫寒,章军,唐晓军,李心.甘草饮片超微粉碎前后甘草酸溶出行为的比较研究[J].中国中药杂志,2003,28(11):1030-1033.
作者姓名:李志猛  王跃生  李晓明  闫寒  章军  唐晓军  李心
作者单位:1. 北京同仁堂股份有限公司,科学研究所,北京,100011
2. 中国中医研究院,中药研究所,北京,100700
3. 中国北京同仁堂(集团)有限责任公司,北京中药二厂,北京,100010
摘    要:目的 :考察超微粉碎前后甘草饮片中甘草酸溶出行为变化规律。方法 :以甘草酸含量为测定指标 ,分别对不同的样品进行测定实验。结果 :超微粉碎后甘草酸的溶出显著提高 ,且粉碎时间越长 ,粒度越细 ,甘草酸溶出越易。结论 :超微粉碎后有助于甘草饮片中甘草酸的溶出 ,粉碎粒度对甘草酸的溶出有显著的影响。

关 键 词:甘草  甘草酸  超微粉碎
文章编号:1001-5302(2003)11-1030-04
收稿时间:2003/9/29 0:00:00
修稿时间:2003年9月29日

Comparative Study of Dissolved Matter of Glycyrrhizic Acid be fore and after Supermicro-pulverization of Radix Glycyrrhizae
LI Zhi-meng ;WANG Yue-sheng ;LI Xiao-ming ;YAN Han ;ZHANG Ju n ;TANG Xiao-jun ;LI Xin.Comparative Study of Dissolved Matter of Glycyrrhizic Acid be fore and after Supermicro-pulverization of Radix Glycyrrhizae[J].China Journal of Chinese Materia Medica,2003,28(11):1030-1033.
Authors:LI Zhi-meng ;WANG Yue-sheng ;LI Xiao-ming ;YAN Han ;ZHANG Ju n ;TANG Xiao-jun ;LI Xin
Institution:Institute of Science, Tong Ren Tang Limited Company, Beijing 100011, China.
Abstract:Objective: To investigate various ac tivities of dissolved matter of glycyrrhizic acid of Radix Glycyrrhizae and the powder by supermicro-pulver i zation. Method: The contents of glycyrrhizic acid in d ifferent samples were tested. Resu lt: The dissolved matter of glycyrrhizic acid was greatly increased by supermic ro-pulverization. The more time used for grinding, the smaller the size of t h e powder, and the easier the glycyrrhizic acid would be dissolved. Co nclusion: Supermicro-pulverization is helpful to the dissolved matter of glycyrrhizic acid of Radix Glycyrrhizae, an d the size of powder exerts great influence on dissolved matter of glycyrrhizic acid.
Keywords:glycyrrhizic acid  Radix Glycyrrhizae  supermicr o-pulverization
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