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色甘酸钠混悬气雾剂与茶碱缓释胶囊治疗中度哮喘的比较
引用本文:李明华,张淑玉,赵畔波,杨本英,翟为民,王美彩.色甘酸钠混悬气雾剂与茶碱缓释胶囊治疗中度哮喘的比较[J].中国新药与临床杂志,1995(3).
作者姓名:李明华  张淑玉  赵畔波  杨本英  翟为民  王美彩
作者单位:山东省青岛中西医结合医院,山东省青岛市黄岛医院
摘    要:84例中度哮喘病人分成2组。色甘酸钠组(男性23例,女性20例,年龄26±s8a)吸入色甘酸钠混悬气雾剂10.5mg,tid。茶碱缓释胶囊组(男性22例,女性19例,年龄27±8a)口服0.25g。bid。2组均连续观察3mo。结果:色甘酸钠在减轻病人慢性症状、改善肺功能和降低气道高反应性等方面优于茶碱缓释胶囊,(P<0.01)。而后药仅可缓解近期症状。

关 键 词:哮喘,色甘酸钠,茶碱,气雾剂,迟效制剂,呼吸功能试验

Disodium cromoglicate aerosol vs theophylline slow-release capsule in treating patients with mederate asthma
LI Ming-Hua,ZHANG Shu-Yu, ZHAO Pan-Bo,YANG Ben-Ying,ZHAI Wei-Min.Disodium cromoglicate aerosol vs theophylline slow-release capsule in treating patients with mederate asthma[J].Chinese Journal of New Drugs and Clinical Remedies,1995(3).
Authors:LI Ming-Hua  ZHANG Shu-Yu  ZHAO Pan-Bo  YANG Ben-Ying  ZHAI Wei-Min
Abstract:Eighty-four patients with moderate asthma were randomly divided into two groups.The Disodium cromoglicate group(M 23,F 20;age 26±s8a)inhaled cromoglycate sodium aerosol 10.5 mg,tid,for 3 mo.Theophylline slow-release capsule group(M22,F 19;age27±8a)received 0.25g,po, bid, for3 mo.Resultes showed that,in contrast to theophylline slow-release capsule group,inhaled cromoglycate aerosol significantly improved clinical chronic symptoms,lung function,and bronchial hyperreactivity(all P<0.01).Theophylline slow-release capsule only improved short-term symptoms.
Keywords:asthma  disodium cromoglicate  theophylline  aerosols  delayed-action preparations  respiratory function tests  
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