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血清视黄醇结合蛋白-4水平与胎儿宫内生长发育的关系
引用本文:刘鹏,张小莉. 血清视黄醇结合蛋白-4水平与胎儿宫内生长发育的关系[J]. 中国妇幼保健, 2011, 26(13): 2033-2035
作者姓名:刘鹏  张小莉
作者单位:山西医科大学儿科系,山西,太原,030013
摘    要:
目的:检测新生儿血清视黄醇结合蛋白-4(RBP-4)的水平,探讨其与胰岛素水平及胎儿宫内生长发育的关系,并对相关因素进行分析。方法:用酶联免疫法检测89例新生儿血清中RBP-4和胰岛素水平,其中小于胎龄组(SGA)30例、适于胎龄组(AGA)30例、大于胎龄组(LGA)29例,并按出生体重评估新生儿宫内的营养状态。结果:①3组间RBP-4及胰岛素水平的差异有统计学意义(P均<0.05)。②血清RBP-4水平与新生儿出生体重呈明显正相关(r=0.943,P<0.01);③胰岛素水平与新生儿出生体重呈明显正相关(r=0.975,P<0.01);④RBP-4水平与胰岛素水平呈明显正相关(r=0.979,P<0.01)。结论:新生儿体内RBP-4水平在一定程度上反映宫内生长发育状态,可能和胰岛素共同参与调节新生儿的生长发育。

关 键 词:视黄醇结合蛋白-4  胰岛素  新生儿  宫内生长发育

Relationship between serum retinol binding protein 4 level and fetal intrauterine growth and development
LIU Peng,ZHANG Xiao-Li. Relationship between serum retinol binding protein 4 level and fetal intrauterine growth and development[J]. Maternal and Child Health Care of China, 2011, 26(13): 2033-2035
Authors:LIU Peng  ZHANG Xiao-Li
Affiliation:LIU Peng,ZHANG Xiao-Li.Department of Pediatrics,Shanxi Medical University,Taiyuan 030013,Shanxi,China
Abstract:
Objective:To detect the serum retinol binding protein 4(RBP-4) level in neonates,explore its relationship with insulin level and fetal intrauterine growth and development,and analyze the related factors.Methods:ELISA was used to detect the serum levels of RBP-4 and insulin in 89 neonates,89 neonates included 30 neonates in small for gestational age(SGA) group,30 neonates in appropriate for gestational age(AGA) group and 29 neonates in large for gestational age(LGA) group,then the intrauterine nutritional co...
Keywords:Retinol binding protein-4  Insulin  Neonate  Intrauterine growth and development  
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