| 伸长细胞型室管膜瘤2例报道及文献复习 |
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| 引用本文： | 杜军,印洪林,陆珍凤,周航波,周晓军. 伸长细胞型室管膜瘤2例报道及文献复习[J]. 临床与实验病理学杂志, 2008, 24(6) |
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| 作者姓名： | 杜军 印洪林 陆珍凤 周航波 周晓军 |
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| 作者单位： | 南京大学医学院临床学院、南京军区南京总医院病理科,南京,210002;南京大学医学院临床学院、南京军区南京总医院病理科,南京,210002;南京大学医学院临床学院、南京军区南京总医院病理科,南京,210002;南京大学医学院临床学院、南京军区南京总医院病理科,南京,210002;南京大学医学院临床学院、南京军区南京总医院病理科,南京,210002 |
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| 摘 要： | 目的探讨伸长细胞型室管膜瘤的病理形态学特征。方法复习2例伸长细胞型室管膜瘤的临床病理资料，对手术切除的肿瘤组织，常规石蜡切片，HE染色，光镜观察，同时进行免疫组织化学标记GFAP、EMA、S-100蛋白、CKpan、Syn、CD34。结果例1位于腰2～3椎管内终丝，临床上主要表现出脊髓压迫症状，如运动及感觉障碍；例2发生于侧脑室，主要表现为头痛、呕吐、视物模糊。病理组织学上肿瘤富于细胞，排列成束状、交织状，细胞胞突细长双极，核异型性小，少数肿瘤细胞围绕血管周围形成室管膜瘤的无核区结构。免疫组化显示肿瘤细胞表达GFAP、EMA、CD99，而S-100蛋白阴性。结论伸长细胞型室管膜瘤是室管膜瘤的一种罕见亚型，病理诊断时尤其应注意与椎管内的神经鞘瘤和星形细胞瘤鉴别。
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| 关 键 词： | 室管膜瘤 伸长细胞 胶质瘤 |
Tanycytic ependymoma: report of two cases and review of the literature |
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| DU Jun,YIN Hong-lin,LU Zhen-feng,ZHOU Hang-bo,ZHOU Xiao-jun. Tanycytic ependymoma: report of two cases and review of the literature[J]. Chinese Journal of Clinical and Experimental Pathology, 2008, 24(6) |
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| Authors: | DU Jun YIN Hong-lin LU Zhen-feng ZHOU Hang-bo ZHOU Xiao-jun |
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| Affiliation: | Department of Pathology;Nanjing University Medical College;Nanjing General Hospital of Nanjing Command;PLA;Nanjing 210002;China |
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| Abstract: | Purpose To study the clinicopathological changes of the tanycytic ependymoma. Methods The clinical and pathological characteristics of tanycytic ependymoma were reviewed in two cases. Routine HE staining and immunohistochemical staining with GFAP, EMA, S-100, CKpan, Syn and CD34 were performed. Results The first case was a 33-year old woman with a L2~3 spinal cord tumor and presented clinical symptoms of spinal cord compression, such as motor and sensory dysfunction. The second patient was a 36-year old man... |
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| Keywords: | ependymoma tanycyt glioma |
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