弥散加权成像对胶质瘤和脑膜瘤的诊断价值

目的探讨弥散加权成像（diffusion—weighted imaging，DWI）及表观弥散系数（apparent diffusion coefficients，ADC）测量对胶质瘤和脑膜瘤的诊断价值。方法对经手术病理证实的17例胶质瘤和20例脑膜瘤患者进行常规MRI序列扫描和DWI检查，对照分析病变的实质部分、周围水肿区以及正常脑组织的ADC值、指数表观弥散系数（eADC）值。结果17例胶质瘤中10例DWI表现为高信号，4例为稍高信号，3例为等信号。20例脑膜瘤中18例DWI表现为等高信号。脑膜瘤、胶质瘤的ADC值和eADC值均与正常的脑组织有统计学差异（P〈0．01），Ⅲ、Ⅳ级胶质瘤实质部分的ADC值及其瘤周水肿区的ADC值明显低于Ⅰ、Ⅱ级胶质瘤（P〈0．05）。结论ADC值难以对胶质瘤和脑膜瘤做出定性诊断，但DWI和ADC值可用于对脑肿瘤的评价，结合两者可提供肿瘤内部功能信息。

Clinical application of DWI in diagnosis of glioma and meningioma

Objective To explore the clinical value of diffusion weighted imaging(DWI)and apparent diffusion coefficients(ADC)measurement in the diagnosis of glioma and meningioma.Methods Seventeen patients with gliomas and twenty patients with meningioma underwent routine MRI scan and DWI.Comparisons of apparent diffusion coefficients(ADC)and exponential diffusion coefficients(eADC)were made among tumor parenchymas,peripheral edema regions and normal tissues.Results Of 17 cases of gliomas,tumor parenchymas of 10,4,3 c...