Increased cystatin C concentration in urine of nephrotic children |
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Authors: | Marcin?Tkaczyk mailto:mtkaczyk@uni.lodz.pl" title=" mtkaczyk@uni.lodz.pl" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author,Micha??Nowicki,Jolanta?Lukamowicz |
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Affiliation: | (1) Department of Nephrology and Dialysis, Polish Mothers Memorial Hospital Research Institute, 281/289 Rzgowska Street, 93–338 ód, Poland;(2) Immunochemistry Laboratory, Polish Mothers Memorial Hospital Research Institute, ód, Poland |
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Abstract: | The aim of this study was to evaluate changes in urine and plasma concentrations of cystatin C in children with a relapse of the idiopathic nephrotic syndrome (INS). The study group comprised 12 children with INS with proteinuria and 12 children in an 8-week remission, both treated with steroids. Twelve healthy children served as controls. Cystatin C was detectable in the urine of children with proteinuria. The study suggests that massive proteinuria may influence renal cystatin C handling. |
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Keywords: | Cystatin C Glomerular filtration rate Nephrotic syndrome |
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