颈动脉窦粥样硬化与冠状动脉粥样硬化程度相关

目的:探讨颈动脉粥样硬化与冠心病程度的关系。方法:对285例可疑冠心病患者行冠脉造影检查,以B型超声仪检查颈动脉内中膜厚度(IM T)。用冠脉病变支数表示冠心病程度。采静脉血检查血脂水平。结果:颈动脉与冠状动脉粥样硬化有共同的危险因子,如增龄、肥胖、血脂异常。比较各组IM T差别发现,颈动脉窦的F值最大(左,右分别为65.64%,63.24%)。颈动脉窦粥样硬化对诊断冠心病的阳性预告值最大(左、右颈动脉窦分别为89.9%,88.8%)。结论:颈动脉窦IM T与冠心病程度明显相关。颈动脉窦IM T可以作为筛选冠心病的指标。

Association between atherosclerotic changes of carotid bifurcation and the extent of coronary atherosclerosis

Objective:To investigate the correlation of carotid atherosclerosis with the presence and severity of coronary artery disease(CAD).Methods:Subjects who underwent coronary angiography for suspected CAD were evaluated by B-mode ultrasound with carotid intima-media thickness(IMT).CAD extent was determined by the number of diseased vessels.Venous blood was sampled for the measurement of serum lipid concentration.Results:Carotid and coronary atherosclerosis shared many risk factors,such as aging,obesity and dyslipidemia.Carotid bifurcation took the maximal F value in the comparison of IMT values among groups(the F of left,right sino-carotid was 65.64%,63.24% respectively).Bifurcation also had the maximal positive predictive value for detecting CAD(the positive predictive valne of left,right sino-carotid was 89.9%,88.8% respectively).Conclusion:IMT in the carotid bifurcation is related significantly with the presence and extent of CAD.Carotid bifurcation IMT may be used as a surrogate marker for coronary atherosclerosis.