居住地地理因素与急性高原反应相关性分析

目的 观察平原健康青年男性暴露于高原环境时急性高原反应(AMS)发病情况,探讨青年男性原居住地地理因素与进入高原后AMS症状学评分之间的相关关系.方法 收集6个不同地区青年男性急进高原(海拔3 680 m)时人群的人口学资料,并进行AMS症状评分.将人群根据是否有AMS分为AMS组与对照组,比较两组间各地理因素的情况.将对象原居住地地理因素与AMS发生进行相关性分析,并应用主成分回归分析探讨影响AMS患者的症状学评分的主要地理因素.结果 相关分析显示,除年平均气温和年平均风速与AMS发病无相关关系外,其余8个指标均差异有统计学意义(P＜0.05).经主成分分析确定了3个主成分因素,累积贡献率为81.39％;以AMS评分为因变量经主成分回归分析得到回归方程.结论 来自不同地域的人群,对高原环境耐受能力存在差异,原居住地海拔越低、平均降雨量越天越容易发生AMS.

Correlation between geographical factors of residence and acute mountain sickness

Objective To investigate the onset situation of acute mountain sickness(AMS) among plain healthy young men exposing to plateau environment and to study the relationship between the geographical factors of original residence place in young males and the symptomatic scores of AMS after entering plateau.Methods The demographic data of young males from 6 different regions when entering into plateau(elevation 3 680 m) were collected and the symptomatic scores of AMS were evaluated.The population was divided into the AMS group and control group according to whether haning AMS.The geographical factors were compared between the two groups.The geographical factors of original residence place and AMS occurrence were performed the correlation analysis.The principal component regression analysis was adopted to analyze the main geographical factors affecting the symptomatic scores of AMS patients.Results The correlation analysis showed that except the annual average temperature and annual mean wind speed had no significant correlation with AMS onset,other 8 indexes had statistical differences (P＜0.05).Three principle components were determined through the principal component regression analysis,its cumulative contribution rate was 81.39 ％,and a regression equation was obtained with AMS score as the dependent variable.Conclusion The ability resistant to plateau environment in the population from different regions is different.The elevation of primary residence place is lower,the mean average rainfall is greater,AMS is easier to occur.