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柴胡疏肝散对慢性束缚应激性肝郁证大鼠的影响
引用本文:熊振芳,朱清静.柴胡疏肝散对慢性束缚应激性肝郁证大鼠的影响[J].中国中西医结合消化杂志,2004,12(4):220-221.
作者姓名:熊振芳  朱清静
作者单位:湖北省中医院肝病中心,武汉,430061
摘    要:目的:研究柴胡疏肝散对慢性束缚应激性肝郁证大鼠的影响.方法:应用慢性束缚应激方法建立肝郁证动物模型,观察大鼠体重、1%蔗糖水摄取量,放射免疫法测定血浆促肾上腺皮质激素(ACTH)水平.结果:柴胡疏肝散能部分对抗应激导致的大鼠体重增长缓慢和高促ACTH,能增加应激大鼠的蔗糖水摄取量.结论:柴胡疏肝散可调节慢性束缚应激模型大鼠的功能紊乱.

关 键 词:肝郁证  柴胡疏肝散

Effect of Chaihu Shugan Powder on Rats with Liver-depression Syndrome Induced by Chronic Restrained Stress
XIONG Zhenfang,ZHU Qingjing Center of Liver Diseases,Affiliated Hospital of Hubei College of TCM,Wuhan.Effect of Chaihu Shugan Powder on Rats with Liver-depression Syndrome Induced by Chronic Restrained Stress[J].Chinese Journal of Integrated Traditional and Western Medicine on Digestion,2004,12(4):220-221.
Authors:XIONG Zhenfang  ZHU Qingjing Center of Liver Diseases  Affiliated Hospital of Hubei College of TCM  Wuhan
Institution:XIONG Zhenfang,ZHU Qingjing Center of Liver Diseases,Affiliated Hospital of Hubei College of TCM,Wuhan 430061
Abstract:Objective: To study the effect of Chaihu Sh ugan Powder(CSP) on rats with liver-depression syndrome induced by chronic stre ss.Methods: Chronic restrained stress(CRS) was a dopted to establish the rat model of liver-depression syndrome. In the experime nt, the body weight of the rats and the consumption of 1% sugar water by the rat s were observed, and the level of ACTH in the plasma of the rats was detected by radioimmunoassay. Results: CSP could antagonize t he loss of weight and the increase of ACTH,and could increase the consumption o f 1% sugar water in rats induced by chronic stress. Conclusion : CSP can regulate the function disorder of rats with liver- depression syndrome induced by chronic restrained stress.
Keywords:liver-depression syndrome  Chaihu Shuga n Powder
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