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经皮冠状动脉介入治疗术后对比剂肾病发病率及危险因素分析
引用本文:杨世诚,陈永利,刘园园,张莹莹,刘晓罡,付乃宽. 经皮冠状动脉介入治疗术后对比剂肾病发病率及危险因素分析[J]. 天津医药, 2011, 39(10): 903-906. DOI: 10.3969/j.issn.0253-9896.2011.10.008
作者姓名:杨世诚  陈永利  刘园园  张莹莹  刘晓罡  付乃宽
作者单位:1. 300070,天津医科大学
2. 300070,天津市胸科医院心内一科
基金项目:天津市卫生局级科技基金攻关课题(项目编号:10KG122)
摘    要:
目的:探讨经皮冠状动脉介入治疗(PCI)术后对比剂肾病(CIN)发病率及危险因素。方法:回顾性分析2008年1月—2010年12月行PCI术患者共1010例,根据CIN诊断标准将其分为CIN组171例(16.9%)和非CIN组839例,比较2组相关因素的差异,应用Logistic回归分析CIN危险因素。结果:2组年龄、血糖、血红蛋白、红细胞、红细胞比容、三酰甘油、胆固醇、高密度脂蛋白、低密度脂蛋白、收缩压、左室射血分数(LVEF)、白蛋白、肌酐清除率(Ccr)、榕血Ccr、对比剂用量差异有统计学意义(P<0.05或P<0.01)。Logistic回归分析显示,年龄≥70岁、心肌梗死、急诊PCI、糖尿病、低血压、贫血、Ccr≤60mL/min、对比剂用量>200mL、LVEF≤0.45是发生CIN的危险因素。结论:CIN是PCI术后常见并发症,对具备CIN危险因素的高危患者应引起临床上高度重视。

关 键 词:血管成形术,经腔,经皮冠状动脉  肾病  危险因素  发病率  Logistic模型  造影剂

The Incidence and Risk Factors for Contrast Induced Nephropathy after Percutaneous Coronary Intervention
YANG Shicheng,CHEN Yongli,LIU Yuanyuan,ZHANG Yingying,LIU Xiaogang,FU Naikuan. The Incidence and Risk Factors for Contrast Induced Nephropathy after Percutaneous Coronary Intervention[J]. Tianjin Medical Journal, 2011, 39(10): 903-906. DOI: 10.3969/j.issn.0253-9896.2011.10.008
Authors:YANG Shicheng  CHEN Yongli  LIU Yuanyuan  ZHANG Yingying  LIU Xiaogang  FU Naikuan
Affiliation:YANG Shicheng,CHEN Yongli,LIU Yuanyuan,ZHANG Yingying,LIU Xiaogang,FU Naikuan Graduate School of Tianjin Medical University,Tianjin 300070,China
Abstract:
Objective: To investigate the incidence and risk factors for contrast induced nephropathy (CIN) after percutaneous coronary intervention (PCI). Methods: A retrospective study was performed on 1 010 patients who had undergone PCI from January 2008 to December 2010. According to the diagnostic criteria for CIN,the patients were divided into CIN group and non-CIN group. The related factors were compared between the two groups. Logistic regression analysis was applied to determine the risk factors for CIN. Resu...
Keywords:angioplasty  transluminal  percutaneous coronary nephrosis risk factors incidence Logistic models contrast media  
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