| 有机硒降小鼠血糖和血脂作用的实验研究 |
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| 引用本文： | 冯润荷,王景申. 有机硒降小鼠血糖和血脂作用的实验研究[J]. 天津医药, 2011, 39(10): 955-956. DOI: 10.3969/j.issn.0253-9896.2011.10.026 |
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| 作者姓名： | 冯润荷 王景申 |
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| 作者单位： | 1. 300222,天津医学高等专科学校
2. 300222,天津市两奈克生物技术有限公司 |
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| 摘 要： | 目的:探讨有机硒对糖尿病小鼠血糖和高脂血症小鼠血脂的影响。方法:小鼠180只随机分为6组,对照1组、糖尿病模型组、治疗1组、对照2组、高脂模型组和治疗2组,每组30例,雌雄各半。治疗组给予有机硒蛋白粉,对照组和疾病模型组给予等容积的自来水,末次给药后取血,测定空腹血糖、血清总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)和高密度脂蛋白胆固醇(HDL-C)水平。结果:治疗结束时糖尿病模型组和治疗1组小鼠血糖均高于对照1组;治疗1组小鼠血糖低于糖尿病模型组。高脂模型组TC、TG、LDL-C和HDL-C均显著高于治疗2组和对照2组;治疗2组血清TC、TG、LDL-C和HDL-C均高于对照2组。结论:有机硒蛋白粉具有显著降低高脂血症小鼠血脂和糖尿病小鼠血糖的作用。
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| 关 键 词： | 有机硒化合物 糖尿病,实验性 高脂血症 血糖 脂类 疾病模型,动物 小鼠 |
Organic Selenium Reduces Blood Glucose and Blood Lipid in Mice |
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| FENG Runhe,WANG Jingshen. Organic Selenium Reduces Blood Glucose and Blood Lipid in Mice[J]. Tianjin Medical Journal, 2011, 39(10): 955-956. DOI: 10.3969/j.issn.0253-9896.2011.10.026 |
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| Authors: | FENG Runhe WANG Jingshen |
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| Affiliation: | FENG Runhe,WANG Jingshen Tianjin Medical College,Tianjin 300222,China |
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| Abstract: | Objective: To investigate the influence of organic selenium on the blood glucose and lipid in diabetes mouse model and hyperlipidemic mouse model. Methods: One hundred and eighty mice were randomly divided into 6 groups, control group 1, diabetic model group, treatment group 1, control group 2, high fat model group and treatment group 2. Mice of treatment group received organic selenium protein powder, and mice of control group and the pathological model group were given same volume of tap water. Blood samp... |
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| Keywords: | organoselenium compounds diabetes mellitus experimental hyperlipidemias blood glucose lipids disease models animal mice |
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