Progressive multifocal leukoencephalopathy in a lung transplant recipient. |
| |
Authors: | David Shitrit Lev Nirit Sheely I Shiran Gabriel Izbicki Dov Sofer Melamed Eldad Mordechai R Kramer |
| |
Institution: | Pulmonary Institute, Rabin Medical Center, Sackler School of Medicine, Tel Aviv University, Petah Tivka, Israel. |
| |
Abstract: | Progressive multifocal leukoencephalopathy (PML) is a sub-acute, demyelinating disease of the brain caused by a human polyomavirus. We describe a patient with the onset of PML 7 months after lung transplantation. The patient was treated with immunosuppressive modulation and cidofovir, a new anti-viral therapy for PML, with stabilization of the symptoms. We also review the 4 additional reports in the literature of PML after heart and lung transplantation. Progressive multifocal leukoencephalopathy may become more prevalent as the population of heart and lung transplantation recipients increases. |
| |
Keywords: | |
|
|