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Sesquiterpenes from Curcuma comosa
Authors:Yang Qu  Fengming Xu  Seikou Nakamura  Hisashi Matsuda  Yutana Pongpiriyadacha  Lijun Wu  Masayuki Yoshikawa
Affiliation:(1) School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, China;(2) Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto 607-8412, Japan;(3) Rajamangala University of Technology Srivijaya, Thungyai, Nakhon Si Thammarat, 80240, Thailand
Abstract:From the dried rhizomes of Curcuma comosa cultivating in Thailand, 26 known sesquiterpenes were isolated: zederone, zederone epoxide, furanodienone, isofuranodienone, 1(10)Z,4Z-furanodiene-6-one, glechomanolide, dehydrocurdione, neocurdione, curdione, 7α-hydroxyneocurdione, 7β-hydroxycurdione, germacrone-1(10),4-diepoxide, germacrone, 13-hydroxygermacrone, curzerenone, curcolonol, alismol, alismoxide, zedoarondiol, isozedoarondiol, procurcumenol, isoprocurcumenol, aerugidiol, zedoalactone B, curcumenone, and curcumadione. Their structures were elucidated on the basis of physicochemical evidence. Among them, glechomanolide, curzerenone, curcolonol, alismol, alismoxide, and zedoarondiol showed no significant optical activities, so they may be artifact products during the isolation or drying process.
Keywords:Curcuma comosa   Zingiberaceae  Sesquiterpenes
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