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持久性豆状角化过度症1例
引用本文:马东来,邓理,方凯. 持久性豆状角化过度症1例[J]. 临床皮肤科杂志, 2005, 34(3): 167-168
作者姓名:马东来  邓理  方凯
作者单位:中国医学科学院、中国协和医科大学北京协和医院皮肤科,北京,100730
摘    要:报告1例持久性豆状角化过度症。患者男,48岁,因双手,足背和双下肢多发性淡红色角化性小丘珍18年就诊。组织病理检查示,表皮局灶性角化过度伴角化不全,其下方表皮萎缩变薄,真皮血管周围有较致密的单一核细胞浸润,外用0.025%维A酸软膏每日2次,2个月后皮损略变平。

关 键 词:豆状角化过度症 持久性
文章编号:1000-4963(2005)03-0167-02
修稿时间:2004-05-08

Hyperkeratosis lenticularis perstans
MA Dong-lai,DENG Li,FANG Kai. Hyperkeratosis lenticularis perstans[J]. Journal of Clinical Dermatology, 2005, 34(3): 167-168
Authors:MA Dong-lai  DENG Li  FANG Kai
Abstract:A case of hyperkeratosis lenticularis perstans is reported. A 48-year-old man presented with the 18-year history of multiple, rufous and small papules on the back of hands and upper and lower legs. Histologic examination showed the foci of compact and eosinophilic hyperkeratosis overlying a thinned stratum malpighii. In the underlying papillary dermis there was a tight mononuclear infiltration. The patient was treated with topical 0.025% tretinoin twice daily for 2 months, which resulted in a slight applanation of the lesions.
Keywords:hyperkeratosis lenticularis perstans  Flegel's disease
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